PTH Receptor 1 antibody

Principal name

PTH Receptor 1 antibody

Alternative names for PTH Receptor 1 antibody

Parathyroid hormone 1 receptor, PTH/PTHrP type I receptor, PTH1R, PTHR, PTHR1, Parathyroid hormone/parathyroid hormone-related peptide receptor

SwissProt ID

P25961 (Rat), P41593 (Mouse), P50133 (Pig), Q03431 (Human), Q1LZF7 (Bovin), Q9TU31 (Canfa)

Gene ID

5745 (PTH1R), 56813 (Pth1r)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Por (Porcine), Bov (Bovine), Can (Canine), Rb (Rabbit)

Available hosts

Rabbit, Mouse

Available applications

Paraffin Sections (P), Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C), Flow Cytometry (F)

Background of PTH Receptor 1 antibody

The parathyroid hormone receptor type 1 (PTHR1) is bound and activated by two peptide hormones: the parathyroid hormone (PTH) secreted by the parathyroid gland and by parathyroid hormone related peptide (PTHrP) which is produced locally in many tissues. Although these two peptides bind the same receptor, they exert different actions. PTH regulates the concentrations of Ca2+, phosphate ions and vitamin D in the blood, stimulates bone formation/resorption and is distributed to the kidneys where it regulates Ca2+ and phosphate transport, and is also detected in the liver. PTHrP, on the other hand, plays a critical role early in development of bone, heart, mammary glands and other tissues, and is detected in the circulation only during lactation and secreted by some tumors. PTHR1 is obviously localized to all areas and tissues where PTH and PTHrP are known to exert their effects (i.e. bone, kidney, blood, heart, etc.). PTHR1 belongs to the superfamily of G-protein coupled receptors. Like all members, PTHR1 has seven transmembrane spanning domains, an extracellular N-terminus and an intracellular C-termil tail. Upon activation, the receptor couples to either Gs and Gq thereby activating adenylate cyclase and phospholipase C (PLC) respectively. In osteosarcoma cells, PTHR1 can also couple Gα. PTH is being used today to treat osteoporosis, as a factor promoting bone formation. Mutations in PTHR1 are associated with Jansen’s disease (hypercalcemia and dwarfism) and Eiken syndrome (cartilage tumors of bone).

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PTH Receptor 1 antibody

AP15713PU PTH Receptor 1 antibody staining of Human Parathyroid. Rabbit Purified Hu P
0.5 ml / €360.00
  Acris Antibodies GmbH

PTH Receptor 1 antibody

AP15713PU PTH Receptor 1 antibody staining of Human Parathyroid. Rabbit Purified Hu P
1 ml / €520.00
  Acris Antibodies GmbH

PTH Receptor 1 antibody

AP15713PU PTH Receptor 1 antibody staining of Human Parathyroid. Rabbit Purified Hu P
0.1 ml / €190.00
  Acris Antibodies GmbH

PTH Receptor 1 antibody

Predicted band size: 66 kDa . Positive control: Jurkat cell lysate. Recommended dilution: 1/500-2000. (Gel: 8%SDS-PAGE Lysate: 40 ug Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Rb WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

PTH Receptor 1 antibody

Western blot analysis of extracts of various cell lines, using PTH1R antibody. Rabbit IgG Purified Hu, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PTH Receptor 1 antibody

Western blot analysis of HepG2 (lanes 1 and 4), mouse liver (lanes 2 and 5) and rat liver (lanes 3 and 6) lysates: 1-3. Anti-Parathyroid Hormone 1 Receptor (extracellular) antibody , (1:200). 4-6. Anti-Parathyroid Hormone 1 Receptor (extracellular) antibody preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

PTH Receptor 1 antibody

Anti-PTHR / PTHR1 antibody IHC of human Bone, Giant Cell Tumor. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Hu P
50 µg / €379.00
  OriGene Technologies, Inc.

PTH Receptor 1 antibody

PTH Receptor 1 Rabbit Purified Hu
50 µg / €379.00
  OriGene Technologies, Inc.

PTH Receptor 1 antibody

Immunohistochemical analysis of paraffin-embedded human kidney tissues using PTH1R antibody Cat.-No AM06494SU-N with DAB staining. Mouse IgG1 4D2 Ascites Hu E, ICC/IF, P, WB
0.1 ml / €400.00
  Acris Antibodies GmbH

PTH Receptor 1 antibody

Immunohistochemistry (IHC) analyzes of PTH/PTHrP-R antibody v in paraffin-embedded human brain muscle tissue. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

PTH Receptor 1 antibody

Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit IgG Purified Hu, Ms, Rt E, ICC/IF, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

PTH Receptor 1 antibody

PTHR1 polyclonal antibody (A02), Lot # 051207JC01 Western Blot analysis of PTHR1 expression in MCF-7 ( Cat # L046V1 ). Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

PTH Receptor 1 antibody

PTH Receptor 1 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

PTH Receptor 1 antibody

Immunohistochemical staining of PTH1R on formalin fixed, paraffin embedded human parathyroid with PTH1R polyclonal antibody. Rabbit Hu P
0.1 ml / €390.00
  Abnova Taiwan Corp.

PTH Receptor 1 antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using PTHR1 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
50 µg / €205.00
  Assay Biotech

PTH Receptor 1 antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using PTHR1 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 mg / €310.00
  Assay Biotech

PTH Receptor 1 antibody

PTH Receptor 1 Rabbit IgG Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €290.00
  Boster Immunoleader

PTH Receptor 1 antibody

Immunohistochemical analysis of PTHR1 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugad compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Bov, Can, Hu, Por ICC/IF, P, WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

PTH Receptor 1 antibody

Immunohistochemical analysis of PTHR1 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugad compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Bov, Can, Hu, Por ICC/IF, P, WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

PTH Receptor 1 antibody

Immunohistochemical analysis of PTHR1 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugad compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Bov, Can, Hu, Por ICC/IF, P, WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

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