PTP4A1 / PRL1 antibody

Principal name

PTP4A1 / PRL1 antibody

Alternative names for PTP4A1 / PRL1 antibody

PRL-1, PTPCAAX1, PTP(CAAXI), Protein tyrosine phosphatase type IVA 1, Protein-tyrosine phosphatase 4a1, Protein-tyrosine phosphatase of regenerating liver 1

SwissProt ID

Q63739 (Mouse), Q78EG7 (Rat), Q93096 (Human)

Gene ID

7803 (PTP4A1), 19243 (Ptp4a1), 29463

Available reactivities

Hu (Human), Ms (Mouse), Can (Canine), Rt (Rat)

Available hosts

Rabbit, Goat, Mouse

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection))

Background of PTP4A1 / PRL1 antibody

PRL-1 is a protein tyrosine phosphatase also know as phosphatase of regenerating liver, Protein tyrosine phosphatase type IVA, member 1, PTPCAAX1 or Hypothetical protein DKFZp779M0721. Protein tyrosine phosphatases play important roles in the regulation of cell growth, development, and differentiation. PRL-1 is one of the most
interesting immediate early growth response genes in regenerating liver. The gene encodes a novel 20-kDa nuclear protein tyrosine phosphatase. Other than the signature sequence for PTPases, PRL-1 is not homologous to either the dual specificity PTPases (cdc25 and MKP-1) or monospecific PTPases. PRL-1 is elevated throughout the major proliferativephase of liver regeneration when hepatocytes and nonparenchymal cells in the liver are rapidly proliferating. PRL-1 isalso expressed at high levels in other proliferating cells including tumor cell lines such as hepatomas. PRL-1-transfected cells showed altered growth characteristics, including a faster doubling time, growth to a greater saturation density, altered morphology,
and evidence of anchorage-independent growth. Overexpression of human PRL-1 in epithelial cells results in tumor formation in nude mice.

General readings

1. Peng Y, Genin A, Spinner NB, Diamond RH, Taub R.
The gene encoding human nuclear protein tyrosine phosphatase, PRL-1. Cloning, chromosomal localization, and identification of an intron enhancer.
J Biol Chem 1998 Jul 3;273(27):17286-95
PMID: 9642300

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PTP4A1 / PRL1 (C-term) antibody

  Goat Polyclonal Antibody against PTP4A1  
TA302743 (1µg/ml) staining of A549 lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Can, Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PTP4A1 / PRL1 antibody

Western blot analysis of PRL1 Cat.-No AP15254PU-N in mouse spleen tissue lysates (35ug/lane). PRL1 Antibody (arrow) was detected using the purified Pab. Rabbit Ig Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

PTP4A1 / PRL1 (C-term) antibody

PTP4A1 / PRL1 Goat Aff - Purified Can, Hu, Ms, Rt E, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

PTP4A1 - human gene knockout kit via CRISPR

PTP4A1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

PTP4A1 - human gene knockout kit via CRISPR

PTP4A1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

PTP4A1 - human gene knockout kit via CRISPR

PTP4A1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Ptp4a1 - mouse gene knockout kit via CRISPR

Ptp4a1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Ptp4a1 - mouse gene knockout kit via CRISPR

Ptp4a1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Ptp4a1 - mouse gene knockout kit via CRISPR

Ptp4a1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Ptp4a1 - mouse gene knockout kit via CRISPR

Ptp4a1 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PTP4A1 / PRL1

  Recombinant protein of human protein tyrosine phosphatase type IVA, member 1 (PTP4A1)  
PTP4A1 / PRL1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

PTP4A1 / PRL1 (2-173, Active Enzyme)

PTP4A1 / PRL1 Human Purified >90% pure as determined by Coomassie-stained SDS gel. E. coli
10 µg / €500.00
  Acris Antibodies GmbH

PTP4A1 / PRL1 (1-170, His-tag)

Recombinant human PTP4A1, 1-170aa, His-tagged Human Purified > 90 % E. coli
0.5 mg / €750.00
  Acris Antibodies GmbH

PTP4A1 / PRL1 (1-170, His-tag)

Recombinant human PTP4A1, 1-170aa, His-tagged Human Purified > 90 % E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, PTP4A1 (mGFP-tagged) - Human protein tyrosine phosphatase type IVA, member 1 (PTP4A1), 200 uL, >10^7 TU/mL

Lenti ORF particles, PTP4A1 (mGFP-tagged) - Human protein tyrosine phosphatase type IVA, member 1 (PTP4A1), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, PTP4A1 (Myc-DDK tagged) - Human protein tyrosine phosphatase type IVA, member 1 (PTP4A1) , 200 uL, >10^7 TU/mL

Lenti ORF particles, PTP4A1 (Myc-DDK tagged) - Human protein tyrosine phosphatase type IVA, member 1 (PTP4A1) , 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Ptp4a1 (GFP-tagged) - Mouse protein tyrosine phosphatase 4a1 (cDNA clone MGC:102117 IMAGE:30538771), 200 uL, >10^7 TU/mL

Lenti ORF particles, Ptp4a1 (GFP-tagged) - Mouse protein tyrosine phosphatase 4a1 (cDNA clone MGC:102117 IMAGE:30538771), 200 uL, >10^7 TU/mL  
200 µl / €790.00
  OriGene Technologies, Inc.

Lenti ORF particles, Ptp4a1 (GFP-tagged) - Mouse protein tyrosine phosphatase 4a1 (cDNA clone MGC:102501 IMAGE:3990529), 200 uL, >10^7 TU/mL

Lenti ORF particles, Ptp4a1 (GFP-tagged) - Mouse protein tyrosine phosphatase 4a1 (cDNA clone MGC:102501 IMAGE:3990529), 200 uL, >10^7 TU/mL  
200 µl / €790.00
  OriGene Technologies, Inc.

Lenti ORF particles, Ptp4a1 (GFP-tagged) - Mouse protein tyrosine phosphatase 4a1 (Ptp4a1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Ptp4a1 (GFP-tagged) - Mouse protein tyrosine phosphatase 4a1 (Ptp4a1), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Ptp4a1 (Myc-DDK-tagged) - Mouse protein tyrosine phosphatase 4a1 (cDNA clone MGC:102117 IMAGE:30538771), 200 uL, >10^7 TU/mL

Lenti ORF particles, Ptp4a1 (Myc-DDK-tagged) - Mouse protein tyrosine phosphatase 4a1 (cDNA clone MGC:102117 IMAGE:30538771), 200 uL, >10^7 TU/mL  
200 µl / €700.00
  OriGene Technologies, Inc.

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