PTPN1 antibody

Principal name

PTPN1 antibody

Alternative names for PTPN1 antibody

Protein Tyrosin Phosphatase , PTP1B, PTP-1B, Tyrosine-protein phosphatase non-receptor type 1, Protein-tyrosine phosphatase 1B

SwissProt ID

O13016 (Chick), P18031 (Human), P20417 (Rat), P35821 (Mouse)

Gene ID

5770 (PTPN1), 11122 (PTPRT)

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Can (Canine), Chk (Chicken), Por (Porcine), Rt (Rat), Ze (Zebrafish), African clawed frog, Mky (Monkey)

Available hosts

Rabbit, Mouse, Chicken

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), ELISA (detection) (E(detection)), Functional assay (FN), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F)

Background of PTPN1 antibody

PTPN1 is the founding member of the protein tyrosine phosphatase (PTP) family. PTPs catalyze the hydrolysis of the phosphate monoesters specifically on tyrosine residues. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP has been shown to act as a negative regulator of insulin signaling by dephosphorylating the phosphotryosine residues of insulin receptor kinase. This PTP was also reported to dephosphorylate epidermal growth factor receptor kinase, as well as JAK2 and TYK2 kinases, which implicated the role of this PTP in cell growth control, and cell response to interferon stimulation.The protein encoded by this gene is the founding member of the protein tyrosine phosphatase (PTP) family, which was isolated and identified based on its enzymatic activity and amino acid sequence. PTPs catalyze the hydrolysis of the phosphate monoesters specifically on tyrosine residues. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP has been shown to act as a negative regulator of insulin signaling by dephosphorylating the phosphotryosine residues of insulin receptor kinase. This PTP was also reported to dephosphorylate epidermal growth factor receptor kinase, as well as JAK2 and TYK2 kinases, which implicated the role of this PTP in cell growth control, and cell response to interferon stimulation. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

Chernoff, J.,et al. (1990) Proc. Natl. Acad. Sci.
USA 87, 2735-2739.

  1. Quick-Filters:
  2. Highly Validated (5)

Items 1 to 20 of 43 total

per page
Page:
  1. 1
  2. 2
  3. 3

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PTPN1 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PTPN1 (RC204902, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PTPN1. Mouse IgG2a OTI1B4 Purified Hu F, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

PTPN1 antibody

Anti-PTPN1 mouse monoclonal antibody (TA503038) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PTPN1(RC204902). Mouse IgG2a OTI1A2 Purified Hu F, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

PTPN1 antibody

Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-PTPN1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503188) Mouse IgG2a OTI2G3 Purified Hu F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

PTPN1 antibody

Immunohistochemical staining of paraffin-embedded Human colon tissue within the normal limits using anti-PTPN1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503310) Mouse IgG2a OTI1D10 Purified Can, Hu, Mky F, ICC/IF, P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

PTPN1 antibody

Immunohistochemical staining of paraffin-embedded Human liver tissue using anti-PTPN1 Rabbit Polyclonal antibody. (TA590672) Rabbit IgG Purified Hu P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PTPN1 antibody

Western blot analysis of PTP1B expression in UV treated COS7 whole cell lysates,The lane on the left is treated with the antigen-specific peptide. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

PTPN1 antibody

Immunohistochemical staining of paraffin-embedded Human tonsil within the normal limits using anti-PTPN1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503309) Mouse IgG2a OTI1C5 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

PTPN1 antibody

Figure 1. Western blot analysis using anti-PTP1b (Cat. #AM11083PU-N) to detect PTP1b in mouse lung tissue lysate (Lane 1) and recombinant PTP1b protein [1-321] (Lane 2) Mouse IgG1 107AT690 Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

PTPN1 antibody

Immunohistochemistry (IHC) analyzes of PTP1B antibody (Cat.-No.: AP06575PU-N) in paraffin-embedded human brain tissue. Rabbit Aff - Purified Hu, Ms P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

PTPN1 antibody

Western blot analysis of anti-PTP1B Antibody in Ramos cell line lysates (35ug/lane). PTP1B (arrow) was detected using the purified Pab. Rabbit Ig Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

PTPN1 antibody

PTPN1 MaxPab polyclonal antibody. Western Blot analysis of PTPN1 expression in human spleen. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

PTPN1 antibody

Western Blot analysis of PTPN1 expression in transfected 293T cell line () by PTPN1 MaxPab polyclonal antibody.

Lane 1: PTPN1 transfected lysate(50.00 KDa).
Lane 2: Non-transfected lysate. Rabbit Serum Hu E(detection), IP, WB
0.1 ml / €380.00
  Abnova Taiwan Corp.

PTPN1 antibody

Western Blot analysis of PTPN1 expression in transfected 293T cell line (H00005770-T01) by PTPN1 MaxPab polyclonal antibody.

Lane 1: PTPN1 transfected lysate(50.00 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

PTPN1 antibody

Immunoblot analysis of cell lysates. Lane 1 : HepG2 cell lysate and lane 2 : 293T cell lysate. Mouse IgG2a 3A7 Hu WB
0.1 ml / €390.00
  Abnova Taiwan Corp.

PTPN1 antibody

PTPN1 Rabbit Hu, Ms E
0.4 ml / €390.00
  Abnova Taiwan Corp.

PTPN1 pSer50 antibody

Immunohistochemistry analysis of paraffin-embedded human brain, using PTP1B (Phospho-Ser50) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
50 µg / €205.00
  Assay Biotech

PTPN1 pSer50 antibody

Immunohistochemistry analysis of paraffin-embedded human brain, using PTP1B (Phospho-Ser50) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €310.00
  Assay Biotech

PTPN1 antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using PTP1B (Ab-50) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
50 µg / €205.00
  Assay Biotech

PTPN1 antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using PTP1B (Ab-50) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €310.00
  Assay Biotech

PTPN1 antibody

Transfected 293T; WB Suggested Anti-PTPN1 Antibody Titration: 0.2-1 ug/ml. Positive Control: Transfected 293T; PTPN1 antibody - middle region (ARP45360_P050) in Transfected 293T cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Can, Chk, Hu, Ms, Por, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

Items 1 to 20 of 43 total

per page
Page:
  1. 1
  2. 2
  3. 3
  • LinkedIn