PTPN23 antibody

Principal name

PTPN23 antibody

Alternative names for PTPN23 antibody

HD-PTP, PTP-TD14, KIAA1471, Tyrosine-protein phosphatase non-receptor type 23, His domain-containing protein tyrosine phosphatase, Protein tyrosine phosphatase TD14

SwissProt ID

O88902 (Rat), Q6PB44 (Mouse), Q9H3S7 (Human)

Gene ID

25930 (PTPN23), 4259300 (chlB)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Paraffin Sections (P), Western blot / Immunoblot (WB), ELISA (detection) (E(detection))

Background of PTPN23 antibody

HD-PTP is a 1,636 amino acid protein encoded by the human gene PTPN23. HD-PTP belongs to the protein-tyrosine phosphatase family, non-receptor class subfamily. It contains one BRO1 domain, two TPR repeats and one tyrosine-protein phosphatase domain. The C-terminal region contains the PTP-like domain, whereas the N-terminal region contains the two TPR regions. These regions are homologous to the yeast protein, BRO1, which is involved in the mitogen-activated protein kinase signaling pathway. Similarly, HD-PTP is believed to act as a negative regulator of Ras-mediated mitogenic activity and is phosphorylated upon DNA damage, probably by ATM or ATR. HD-PTP protein is differentially modulated by two angiogenic growth factors. While Vascular Endothelial Growth Factor (VEGF) has no affect on protein levels, Fibroblast Growth Factor-2 (FGF-2) induces HD-PTP degradation via the proteasome system.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PTPN23 antibody

Western Blot analysis of PTPN23 expression in transfected 293T cell line (H00025930-T02) by PTPN23 MaxPab polyclonal antibody.

Lane 1: PTPN23 transfected lysate(63.47 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

PTPN23 antibody

Immunohistochemistry-Paraffin: PTPN23 Antibody [NBP1-84158] Immunohistochemical staining of human appendix shows cytoplasmic positivity in glandular cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PTPN23

PTPN23 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

PTPN23

PTPN23 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

PTPN23 293T Cell Transient Overexpression Lysate(Denatured)

PTPN23 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

5 Item(s)

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