PTPN9 antibody

Principal name

PTPN9 antibody

Alternative names for PTPN9 antibody

PTPase MEG2, Tyrosine-protein phosphatase non-receptor type 9, Protein-tyrosine phosphatase MEG2

SwissProt ID

O35239 (Mouse), P43378 (Human), Q641Z2 (Rat)

Gene ID

5780 (PTPN9), 5357808 (ackA)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of PTPN9 antibody

MEG-2 also known as PTPN9 is a protein-tyrosine phosphatase originally isolated from peripheral neutrophilic polymorphonuclear leukocytes (PMN). MEG2 is predominantly cytosolic with components present in secondary and tertiary granules and secretory vesicles. MEG2 activity is inhibited after exposure of cells to opsonized zymosan or to phorbol 12-myristate 13-acetate but largely unaffected by the f-met-leu-phe (N-formyl-methionyl-leucyl-phenyalanine). Cysteine 515 is essential for catalytic activity of MEG-2, whereas the noncatalytic (N-terminal) domain of MEG2 negatively regulates the enzymatic activity of the C-terminal phosphatase domain. The activity of MEG2 is enhanced by specific polyphosphoinositides. MEG2 associates at an early stage with nascent phagosomes. MEG2 is a polyphosphoinositide-activated tyrosine phosphatase that may be involved in signaling events regulating phagocytosis, and essential antimicrobial function in the immune response.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PTPN9 (C-term) antibody

Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with MEG2 antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Rabbit Ig Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

PTPN9 antibody

PTPN9 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

PTPN9 antibody

PTPN9 Mouse IgG2a 2F12 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

PTPN9 antibody

Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with PTPN9 polyclonal antibody ( Cat # PAB4083 ) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Hu E, P, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

PTPN9 antibody

Immunohistochemistry-Paraffin: PTPN9 Antibody [NBP1-81243] Immunohistochemical staining of human stomach, lower shows strong cytoplasmic and membranous positivity in glandular cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PTPN9 (Active Enzyme)

PTPN9 Human Purified >90% pure as determined by Coomassie-stained SDS gel E. coli
20 µg / €490.00
  Acris Antibodies GmbH

PTPN9

PTPN9 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

PTPN9

PTPN9 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

PTPN9

PTPN9 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

PTPN9

PTPN9 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

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