PTPRA antibody

Principal name

PTPRA antibody

Alternative names for PTPRA antibody

PTPA, PTP alpha, R-PTP-alpha, PTPRL2, Protein-tyrosine phosphatase alpha, Receptor-type tyrosine-protein phosphatase alpha

SwissProt ID

P18052 (Mouse), P18433 (Human), Q03348 (Rat)

Gene ID

5786 (PTPRA)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Chk (Chicken), Ze (Zebrafish), African clawed frog, Mky (Monkey), Rb (Rabbit), Sh (Sheep), Eq (Equine), Hst (Hamster), Por (Porcine), Gorilla, Xen (Xenopus)

Available hosts

Rabbit

Available applications

Paraffin Sections (P), Enzyme Immunoassay (E), Western blot / Immunoblot (WB)

Background of PTPRA antibody

Phosphorylation of receptors by protein kinases is a process that can be reversed by a group of enzymes called protein phosphatases. Coordinated control of kinases and phosphatases provides the cell with the capacity to rapidly switch between phosphorylated and dephosphorylated protein states in dynamic response to environmental stimuli. Activation of critical enzymes by kinase phosphorylation alone is not enough to provide adequate regulation ? it is the combination with phosphatase dephosphorylation that effectively creates on/off switches to control cellular events. Errors in control, either through kinases or their counterpart phosphatases, can lead to unchecked cell growth attributable to human cancers and developmental disorders. Potential mechanisms to control dephosphorylation include changes in the expression of protein phosphatases, their subcellular localization, phosphorylation of phosphatase catalytic and regulatory subunits and regulation by endogenous phosphatase inhibitors. Most protein phosphatases are not stringently specific for their substrates. Consequently, changes in phosphatase activity may have a broad impact on dephosphorylation and turnover of phosphoproteins that are substrates for different kinases. This may be an important point of control to connect cellular circuitry of interrelated signaling pathways, and to synchronize physiological responses.

19 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PTPRA (Cytopl. Dom.) antibody

Anti-PTPRA antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 10 ug/ml. Rabbit Aff - Purified Hu P
50 µg / €345.00
  OriGene Technologies, Inc.

PTPRA (Cytoplasm. Dom.) antibody

Anti-PTPRA antibody IHC of human breast, epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 4 ug/ml. Rabbit Aff - Purified Hu P
50 µg / €345.00
  OriGene Technologies, Inc.

PTPRA antibody

Anti-PTPRA antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 4 ug/ml. Rabbit IgG Purified Gorilla, Hu, Mky, Rt
50 µg / €345.00
  OriGene Technologies, Inc.

PTPRA (N-term) antibody

The anti-PTPalpha N-term Pab is used in Western blot to detect PTPalpha in mouse brain tissue lysate. Rabbit Ig Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

PTPRA antibody

The PTPRA polyclonal antibody ( Cat # PAB4090 ) is used in Western blot to detect PTPRA in mouse brain tissue lysate. Rabbit Hu, Ms E, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

PTPRA pTyr798 antibody

Western blot analysis of extracts from HeLa cells treated with serum 20% 15', using PTPRA (Phospho-Tyr798) Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
50 µg / €205.00
  Assay Biotech

PTPRA pTyr798 antibody

Western blot analysis of extracts from HeLa cells treated with serum 20% 15', using PTPRA (Phospho-Tyr798) Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €310.00
  Assay Biotech

PTPRA antibody

Human 293T; WB Suggested Anti-PTPRA Antibody Titration: 0.2-1 ug/ml. Positive Control: 293T cell lysate. PTPRA is supported by BioGPS gene expression data to be expressed in HEK293T.; PTPRA antibody - C-terminal region (ARP45366_P050) in Human 293T cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Can, Chk, Hu, Ms, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

PTPRA pTyr798 antibody

Western blot analysis of PTP alpha (pY798) expression in HT29 (A); NIH3T3 (B) whole cell lysates. Rabbit Aff - Purified Can, Chk, Hu, Mky, Ms, Rb, Rt, Sh, Ze WB
30 µl / €210.00
  Cohesion Biosciences Ltd.

PTPRA pTyr798 antibody

Western blot analysis of PTP alpha (pY798) expression in HT29 (A); NIH3T3 (B) whole cell lysates. Rabbit Aff - Purified Can, Chk, Hu, Mky, Ms, Rb, Rt, Sh, Ze WB
0.1 ml / €330.00
  Cohesion Biosciences Ltd.

PTPRA pTyr798 antibody

Western blot analysis of PTP alpha (pY798) expression in HT29 (A); NIH3T3 (B) whole cell lysates. Rabbit Aff - Purified Can, Chk, Hu, Mky, Ms, Rb, Rt, Sh, Ze WB
0.2 ml / €530.00
  Cohesion Biosciences Ltd.

PTPRA antibody

Western Blot: PTP alpha Antibody [NBP1-62456] - This Anti-PTPRA antibody was used in Western Blot of 293T tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu, Ms, Rt WB
50 µg / €440.00
  Novus Biologicals Inc.

PTPRA antibody

Immunohistochemistry-Paraffin: PTP alpha Antibody [NBP1-89683] - Immunohistochemical staining of human heart muscle shows strong cytoplasmic positivity in myocytes. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

PTPRA antibody

PTPRA Rabbit Aff - Purified Hu P
50 µl / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PTPRA (transcript variant 3)

PTPRA Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

PTPRA (transcript variant 1)

PTPRA Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

PTPRA overexpression lysate

PTPRA overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

PTPRA overexpression lysate

PTPRA overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

PTPRA overexpression lysate

PTPRA overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

19 Item(s)

per page
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