PTPRB antibody

Principal name

PTPRB antibody

Alternative names for PTPRB antibody

PTPB, VE-PTP, R-PTP-beta, Receptor-type tyrosine-protein phosphatase beta, Protein-tyrosine phosphatase beta

SwissProt ID

B2RU80 (Mouse), D3ZE19 (Rat), P23467 (Human)

Gene ID

5787 (PTPRB), 19263

Available reactivities

Rt (Rat), Hu (Human)

Available hosts

Mouse, Rabbit

Available applications

Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Western blot / Immunoblot (WB), Enzyme Immunoassay (E)

Background of PTPRB antibody

PTP beta, also known as Receptor-type tyrosine-protein phosphatase beta [Precursor], Protein-tyrosine phosphatase beta,R-PTP-beta, PTPRB or PTPB is a protein tyrosine phosphatase and is overexpressed in glioblastoma tumors. PTP beta plays a n important functional role in tumor cell migration and adhesion. Glioblastomas express at least three splice variants of PTPbeta, including long and short receptor forms. The short form of PTPbeta lacks exon 12, which encodes 860 amino acids located in the extracellular domain. In normal brain tissue and graded astrocytomas the long and short PTPbeta forms have an overlapping expression pattern. U87 stable cell lines overexpressing long or short PTPbeta migrate faster and adhere more robustly than parental U87 cells. The involvement of long and short PTPbeta in glioma tumor cell biology also contributes to the value of PTPbeta as a cancer target.

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Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PTPRB (transcript variant 1)

  Recombinant protein of human protein tyrosine phosphatase, receptor type, B (PTPRB), transcript variant 1  
PTPRB Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €788.00
  OriGene Technologies, Inc.

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