PTPRG / PTPG antibody

Principal name

PTPRG / PTPG antibody

Alternative names for PTPRG / PTPG antibody

Receptor-type tyrosine-protein phosphatase gamma

SwissProt ID

P23470 (Human), Q05909 (Mouse), Q98936 (Chick)

Gene ID

5793 (PTPRG), 19270 (Ptprg)

Available reactivities

Hu (Human), Ms (Mouse)

Available hosts

Rabbit

Available applications

Enzyme Immunoassay (E), Paraffin Sections (P), Western blot / Immunoblot (WB)

Background of PTPRG / PTPG antibody

RPTP gamma, also known as Receptor-type tyrosine-protein phosphatase gamma, R-PTP-gamma or PTPRG is a protein tyrosine phosphatase (PTP) is a candidate tumor suppressor gene since it is located on human chromosome 3p14.2-p21, a region frequently deleted in certain types of renal and lung carcinomas. In situ hybridization analysis reveals that RPTP gamma mRNA is expressed in specific regions of the brain and that the localization of RPTP gamma changes during brain development. RPTP gamma is composed of a putative extracellular domain, a single transmembrane domain, and a cytoplasmic portion with two tandem catalytic tyrosine phosphatase domains. The extracellular domain contains a stretch of 266 amino acids with striking homology to the zinc-containing enzyme carbonic anhydrase (CAH), indicating that RPTP gamma and RPTP beta (HPTP zeta) represent a subfamily of receptor tyrosine phosphatases. RPTP gamma may have a function other than catalysis of hydration of metabolic CO2.

General readings

Rose, J.E., et al. Mol. Med. 16 (7-8): 247-253 (2010)
Shu, S.T., et al. Anticancer Res. 30(6): 1937-1946 (2010)
Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34(5): 800-812 (2010)
Bouyain, S., et al. Proc. Natl. Acad. Sci. U.S.A. 107(6): 2443-2448 (2010)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PTPRG / PTPG (765-782) antibody

Figure 1. Staining PTPRG in Skeletal Muscle by Immunohistochemistry using Formalin-Fixed Paraffin-Embedded (FFPE) tissue. Rabbit Purified Hu E, P
50 µg / €470.00
  Acris Antibodies GmbH

PTPRG / PTPG (Center) antibody

The anti-PTPgamma Center Pab is used in Western blot to detect PTPgamma in mouse brain tissue lysate. Rabbit Ig Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

PTPRG / PTPG (Center) antibody

Western blot analysis in mouse lung tissue lysates (35ug/lane) using PTPRG / PTPG antibody Cat.-No. AP53515PU-N. This demonstrates the PTPRG antibody detected the PTPRG protein (arrow). Rabbit Ig Aff - Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

Ptprg - mouse gene knockout kit via CRISPR

Ptprg - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Ptprg - mouse gene knockout kit via CRISPR

Ptprg - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Ptprg - mouse gene knockout kit via CRISPR

Ptprg - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Ptprg - mouse gene knockout kit via CRISPR

Ptprg - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PTPRG / PTPG (Active Enzyme, GST-tagged)

PTPRG / PTPG Human Purified >90% pure as determined by Coomassie-stained SDS gel. E. coli
20 µg / €500.00
  Acris Antibodies GmbH

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Ptprg (GFP-tagged) - Mouse protein tyrosine phosphatase, receptor type, G (Ptprg), 200 uL, >10^7 TU/mL

Lenti ORF particles, Ptprg (GFP-tagged) - Mouse protein tyrosine phosphatase, receptor type, G (Ptprg), 200 uL, >10^7 TU/mL  
200 µl / €2,360.00
  OriGene Technologies, Inc.

Lenti ORF particles, Ptprg (Myc-DDK-tagged) - Mouse protein tyrosine phosphatase, receptor type, G (Ptprg), 200 uL, >10^7 TU/mL

Lenti ORF particles, Ptprg (Myc-DDK-tagged) - Mouse protein tyrosine phosphatase, receptor type, G (Ptprg), 200 uL, >10^7 TU/mL  
200 µl / €2,130.00
  OriGene Technologies, Inc.

10 Item(s)

per page
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