PTPRM antibody

Principal name

PTPRM antibody

Alternative names for PTPRM antibody

PTPRL1, R-PTP-mu, RPTPU, Receptor-type tyrosine-protein phosphatase mu, Protein-tyrosine phosphatase mu

SwissProt ID

P28827 (Human), P28828 (Mouse)

Gene ID

5797 (PTPRM)

Available reactivities

Hu (Human), Bov (Bovine), Ms (Mouse), Rt (Rat), Can (Canine), Bt (Bat), Eq (Equine), Mky (Monkey), Rb (Rabbit), Gorilla, Hst (Hamster), Xen (Xenopus), GP (Guinea Pig), Ze (Zebrafish)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of PTPRM antibody

PTP-mu (Protein tyrosine phosphatase mu) is a receptor type protein tyrosine phosphatase with a predicted molecular weight of 162 kDa that migrates in SDS-PAGE as a 200 kDa protein and undergoes a processing step to generate a functional phosphatase of ~100 kDa. There are 13 potential N-glycosylation sites in the sequence. The primary function of the protein appears to be to mediate cell aggregation. The human gene has been mapped to chromosome 18pter-q11, a region that is frequently associated with abnormalities in cancers. PTP-mu has been shown to be highly expressed in the nervous system where it is found in a complex with N-cadherin and promotes neurite outgrowth. In other studies, PTP-mu has been shown to be expressed in vascular endothelial beds but not in the endocardium. PTP-mu has now been shown to be associated with E- and R-cadherins as well as with the aforementioned N-cadherin although earlier studies failed to demonstrate such associations. Protein tyrosine phosphatases in general and PTP-mu in particular may be important in regulating the adhesion and aggregation of cancer cells particularly in light of the observations that different cancers display differential expression of protein tyrosine phosphatases.

16 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PTPRM (Internal Region) antibody

Anti-PTPRM antibody IHC of human retina. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Bear, Bov, Bt, Can, Chk, Elephant, Eq, Hst, Hu, Mky, Ms, Op, Prim, Rb, Rt P
50 µg / €345.00
  OriGene Technologies, Inc.

PTPRM (Internal Region) antibody

Anti-PTPRM antibody IHC of human retina. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Bear, Bov, Bt, Eq, Hst, Hu, Mky, Ms, Op, Prim, Rb, Rt P
50 µg / €345.00
  OriGene Technologies, Inc.

PTPRM antibody

Predicted cell location: Cytoplasm. Positive control: Human breast and lung cancer tissue. Recommended dilution: 1/50-200  The image on the left is immunohistochemistry of paraffin-embedded human breast and lung cancer tissue using PTPRM antibody at dilution 1/40, on the right is treated with the synthetic peptide. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

PTPRM antibody

Predicted cell location: Cytoplasm. Positive control: Human esophagus and ovarian cancer tissue. Recommended dilution: 1/100-300  The image on the left is immunohistochemistry of paraffin-embedded human esophagus cancer tissue using PTPRM antibody at dilution 1/80, on the right is treated with the synthetic peptide. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

PTPRM antibody

Anti-PTPRM antibody IHC of human eye, retina. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Purified Hu
50 µg / €379.00
  OriGene Technologies, Inc.

PTPRM antibody

Anti-PTPRM antibody IHC of human eye, retina. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Purified Bov, Hu, Ms, Xen
50 µg / €379.00
  OriGene Technologies, Inc.

PTPRM antibody

Host: Rabbit; Target Name: PTPRM; Sample Tissue: 293T Whole Cell lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

PTPRM antibody

PTPRM Mouse IgG1 SBK10 Purified Bov, Hu, Ms, Rt WB
0.1 mg / €360.00
  Acris Antibodies GmbH

PTPRM antibody

PTPRM Mouse IgG1 SK15 Purified Hu IP, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

PTPRM antibody

PTPRM Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

PTPRM antibody

PTPRM Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

PTPRM antibody

PTPRM Goat Hu, Ms E
0.1 mg / €390.00
  Abnova Taiwan Corp.

PTPRM antibody

PTPRM Rabbit Aff - Purified Hu P
50 µg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PTPRM

PTPRM Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

PTPRM

PTPRM Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

PTPRM overexpression lysate

PTPRM overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

16 Item(s)

per page
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