PTPRN antibody

Principal name

PTPRN antibody

Alternative names for PTPRN antibody

R-PTP-N, Islet cell antigen 512, ICA512, ICA3, PTP IA-2, Receptor-type tyrosine-protein phosphatase-like N

SwissProt ID

P56722 (Bovin), Q16849 (Human), Q60673 (Mouse), Q63259 (Rat)

Gene ID

5798 (PTPRN), 19275

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Mky (Monkey)

Available hosts

Rabbit, Mouse, Goat, Chicken

Available applications

Enzyme Immunoassay (E), Immunoprecipitation (IP), Paraffin Sections (P), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of PTPRN antibody

Implicated in neuroendocrine secretory processes. May be involved in processes specific for neurosecretory granules. such as their biogenesis. trafficking or regulated exocytosis or may have a general role in neuroendocrine functions. Seems to lack intrinsic enzyme activity. May play a role in the regulation of secretory granules via its interaction with SNTB2. The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth. differentiation. mitotic cycle. and oncogenic transformation. This PTP possesses an extracellular region. a single transmembrane region. and a single catalytic domain. and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera. and thus may be a potential target of autoimmunity in diabetes mellitus.

General readings

Buzzetti R, Di Pietro S, Giaccari A, Petrone A, Locatelli M, Suraci C, Capizzi M, Arpi ML, Bazzigaluppi E, Dotta F, Bosi E; Non Insulin Requiring Autoimmune Diabetes Study Group. High titer of autoantibodies to GAD identifies a specific phenotype of adult-onset autoimmune diabetes. Diabetes Care. 2007 Apr;30(4):932-8. PMID: 17392553

19 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PTPRN antibody

TA303345 (0.5µg/ml) staining of NIH 3T3 lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Ms E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PTPRN antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PTPRN (RC220230, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PTPRN. Rabbit IgG Purified Hu, Mky, Ms E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PTPRN antibody

Human Pancreas, Islets of Langerhans: Formalin-Fixed, Paraffin-Embedded (FFPE) Mouse IgG2a 8E3 Purified Hu E, P, WB
50 µg / €530.00
  Acris Antibodies GmbH

PTPRN antibody

Western Blot analysis of PTPRN expression in transfected 293T cell line (H00005798-T01) by PTPRN MaxPab polyclonal antibody.

Lane 1: PTPRN transfected lysate(65.01 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

PTPRN antibody

Western Blot analysis of PTPRN expression in transfected 293T cell line (H00005798-T02) by PTPRN MaxPab polyclonal antibody.

Lane 1: PTPRN transfected lysate(104.5 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

PTPRN antibody

PTPRN Rabbit Serum Hu E(detection), IP, WB
0.1 ml / €380.00
  Abnova Taiwan Corp.

PTPRN antibody

Western Blot analysis of PTPRN expression in transfected 293T cell line (H00005798-T03) by PTPRN MaxPab polyclonal antibody.

Lane 1: PTPRN transfected lysate(102.80 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

PTPRN antibody

PTPRN Mouse IgG2a 8E3 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

PTPRN antibody

Immunoblot analysis of cell lysates.
Lane 1 : Bosc23 cell lysate.
Lane 2 : Bosc23 cell lysate transfected with Myc/His/Tau ( 1-441 a. a. ).
Lane 3 : Bosc23 cell lysate transfected with Myc/His/PTPRN ( 709-979 a. a. ).
Lane 4 : Bosc23 cell lysate transfected with GFP-Ubiquitin+1. Mouse AFT38 Hu E, WB
0.1 ml / €390.00
  Abnova Taiwan Corp.

PTPRN antibody

Human HepG2; WB Suggested Anti-PTPRN Antibody Titration: 0.0625ug/ml. Positive Control: HepG2 cell lysate; PTPRN antibody - middle region (ARP45381_P050) in Human HepG2 cells using Western Blot Rabbit Purified Bov, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

PTPRN antibody

PTPRN Rabbit Hu E, P, WB
50 µg / €440.00
  Novus Biologicals Inc.

PTPRN antibody

NBP1-00134(0.5ug/ml) staining of NIH 3T3 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence Goat IgG Aff - Purified Ms E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

PTPRN antibody

Immunohistochemistry-Paraffin: PTPRN Antibody [NBP1-83128] Immunohistochemical staining of human pancreas shows strong cytoplasmic positivity in islet cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PTPRN (full length, C-term DDK tag, transcript variant 1)

PTPRN Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
20 µg / €399.00
  OriGene Technologies, Inc.

PTPRN (C-term DDK tag, transcript variant 1)

PTPRN Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
20 µg / €399.00
  OriGene Technologies, Inc.

PTPRN

PTPRN Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

PTPRN

PTPRN Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Antibody Pairs

Catalog No.    

PTPRN (Human) IP-WB Antibody Pair

PTPRN (Human) IP-WB Antibody Pair  
1 set / €710.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

PTPRN 293T Cell Transient Overexpression Lysate(Denatured)

PTPRN 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

19 Item(s)

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