PTPRN2 antibody

Principal name

PTPRN2 antibody

Alternative names for PTPRN2 antibody

R-PTP-N2, ICAAR, IAR, IA-2beta, Phogrin, KIAA0387, Receptor-type tyrosine-protein phosphatase N2, Islet cell autoantigen-related protein

SwissProt ID

P80560 (Mouse), Q63475 (Rat), Q92932 (Human)

Gene ID

5799 (PTPRN2), 29714 (Ptprn2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Paraffin Sections (P), Immunoprecipitation (IP)

Background of PTPRN2 antibody

The protein encoded by the PTPRN2 gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. The catalytic domain of this PTP is most closely related to PTPRN/IA-2beta. This PTP and PTPRN are both found to be major autoantigens associated with insulin-dependent diabetes mellitus. Three alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported.

General readings

Bailey, S.D., et al. Diabetes Care 33(10): 2250-2253 (2010)
Rose, J.E., et al. Mol. Med. 16 (7-8): 247-253 (2010)
Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34(5): 800-812 (2010)
Yoshida, T., et al. Int. J. Mol. Med. 25(4): 649-656 (2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5): 628-642 (2009)

17 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PTPRN2 antibody

  Rabbit polyclonal anti-PTPRN2 antibody  
Western blot analysis of extracts from NIH/3T3 cells, using PTPRN2 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

PTPRN2 (N-term) antibody

The anti-PTPIA2 beta N-term Pab is used in Western blot to detect PTPIA2 beta in C6 cell lysate. Rabbit Ig Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

PTPRN2 (N-term) antibody

Western blot analysis in A2058 cell line lysates (35ug/lane) using PTPRN2 antibody Cat.-No. AP53516PU-N. This demonstrates the PTPRN2 antibody detected the PTPRN2 protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

PTPRN2 - human gene knockout kit via CRISPR

PTPRN2 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

PTPRN2 - human gene knockout kit via CRISPR

PTPRN2 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

PTPRN2 - human gene knockout kit via CRISPR

PTPRN2 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

PTPRN2 - human gene knockout kit via CRISPR

PTPRN2 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PTPRN2 (transcript variant 2)

  Recombinant protein of human protein tyrosine phosphatase, receptor type, N polypeptide 2 (PTPRN2), transcript variant 2  
PTPRN2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

PTPRN2 overexpression lysate

PTPRN2 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, PTPRN2 (mGFP-tagged)-Human protein tyrosine phosphatase, receptor type, N polypeptide 2 (PTPRN2), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, PTPRN2 (mGFP-tagged)-Human protein tyrosine phosphatase, receptor type, N polypeptide 2 (PTPRN2), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €2,060.00
  OriGene Technologies, Inc.

Lenti ORF particles, PTPRN2 (mGFP-tagged) - Human protein tyrosine phosphatase, receptor type, N polypeptide 2 (PTPRN2), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, PTPRN2 (mGFP-tagged) - Human protein tyrosine phosphatase, receptor type, N polypeptide 2 (PTPRN2), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €2,040.00
  OriGene Technologies, Inc.

Lenti ORF particles, PTPRN2 (mGFP-tagged) - Human protein tyrosine phosphatase, receptor type, N polypeptide 2 (PTPRN2), transcript variant 3, 200 uL, >10^7 TU/mL

Lenti ORF particles, PTPRN2 (mGFP-tagged) - Human protein tyrosine phosphatase, receptor type, N polypeptide 2 (PTPRN2), transcript variant 3, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, PTPRN2 (Myc-DDK-tagged)-Human protein tyrosine phosphatase, receptor type, N polypeptide 2 (PTPRN2), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, PTPRN2 (Myc-DDK-tagged)-Human protein tyrosine phosphatase, receptor type, N polypeptide 2 (PTPRN2), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,860.00
  OriGene Technologies, Inc.

Lenti ORF particles, PTPRN2 (Myc-DDK tagged) - Human protein tyrosine phosphatase, receptor type, N polypeptide 2 (PTPRN2), transcript variant 2 , 200 uL, >10^7 TU/mL

Lenti ORF particles, PTPRN2 (Myc-DDK tagged) - Human protein tyrosine phosphatase, receptor type, N polypeptide 2 (PTPRN2), transcript variant 2 , 200 uL, >10^7 TU/mL  
200 µl / €1,840.00
  OriGene Technologies, Inc.

Lenti ORF particles, PTPRN2 (Myc-DDK tagged) - Human protein tyrosine phosphatase, receptor type, N polypeptide 2 (PTPRN2), transcript variant 3 , 200 uL, >10^7 TU/mL

Lenti ORF particles, PTPRN2 (Myc-DDK tagged) - Human protein tyrosine phosphatase, receptor type, N polypeptide 2 (PTPRN2), transcript variant 3 , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Ptprn2 (GFP-tagged ORF) - Rat protein tyrosine phosphatase, receptor type, N polypeptide 2 (Ptprn2), 200 uL, >10^7 TU/mL

Lenti ORF particles, Ptprn2 (GFP-tagged ORF) - Rat protein tyrosine phosphatase, receptor type, N polypeptide 2 (Ptprn2), 200 uL, >10^7 TU/mL  
200 µl / €2,120.00
  OriGene Technologies, Inc.

Lenti ORF particles, Ptprn2 (Myc-DDK-tagged ORF) - Rat protein tyrosine phosphatase, receptor type, N polypeptide 2 (Ptprn2), 200 uL, >10^7 TU/mL

Lenti ORF particles, Ptprn2 (Myc-DDK-tagged ORF) - Rat protein tyrosine phosphatase, receptor type, N polypeptide 2 (Ptprn2), 200 uL, >10^7 TU/mL  
200 µl / €1,908.00
  OriGene Technologies, Inc.

17 Item(s)

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