PTPRR antibody

Principal name

PTPRR antibody

Alternative names for PTPRR antibody

ECPTP, PTPRQ, R-PTP-R, PCPTP1, Ch-1PTPase, NC-PTPCOM1, Receptor-type tyrosine-protein phosphatase R,Protein-tyrosine phosphatase PCPTP1

SwissProt ID

O08617 (Rat), Q15256 (Human), Q62132 (Mouse)

Gene ID

5801 (PTPRR), 19279 (Ptprr)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Ms (Mouse), Rt (Rat), African clawed frog, Ze (Zebrafish)

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Paraffin Sections (P), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Frozen Sections (C)

Background of PTPRR antibody

PTPRR is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domains, and thus represents a receptor-type PTP.The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domains, and thus represents a receptor-type PTP. The similar gene predominately expressed in mouse brain was found to associate with, and thus regulate the activity and cellular localization of MAP kinases. The rat counterpart of this gene was reported to be regulated by the nerve growth factor, which suggested the function of this gene in neuronal growth and differentiation. Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, and an RNA component, encoded by this gene, that serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres. Deregulation of telomerase expression in somatic cells may be involved in oncogenesis. Studies in mouse suggest that telomerase also participates in chromosomal repair, since de novo synthesis of telomere repeats may occur at double-stranded breaks. Mutations in this gene cause autosomal dominant dyskeratosis congenita, and may also be associated with some cases of aplastic anemia.

General readings

Eswaran,J., (2006) Biochem. J. 395 (3), 483-491

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18 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PTPRR (58-72) antibody

Human Placenta (formalin-fixed, paraffin-embedded) stained with PTPRR antibody AP22761PU-N followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Rabbit Purified Hu E, P
50 µg / €470.00
  Acris Antibodies GmbH

PTPRR antibody

Anti-PTPRR antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. Rabbit Purified Hu E, P
50 µg / €345.00
  OriGene Technologies, Inc.

PTPRR antibody

Figure 3: Immunolocalization of PTPRR protein in Mouse brain. 
Brain cryosections were stained using a mixture of three different monoclonal
antibodies (1E3, 3E11 and 6A6) immunoreactive towards the common part in
PTPRR isoforms and that cross-react with STEP. 
Positive staining is observed in the Purkinje cells of the cerebellum (A), both the neurones and neuropil of the striatum (B). The staining of the striatum reflects STEP immunoreactivity. Mouse IgG2a 6A6 Purified Ms C, IP, WB
0.1 mg / €500.00
  Acris Antibodies GmbH

PTPRR (N-term) antibody

Formalin-fixed and paraffin-embedded human brain tissue reacted with hPCPTP1-Y249, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

PTPRR antibody

Western Blot analysis of PTPRR expression in transfected 293T cell line (H00005801-T01) by PTPRR MaxPab polyclonal antibody.

Lane 1: PTPRR transfected lysate(72.27 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

PTPRR antibody

Proximity Ligation Analysis (PLA) of protein-protein interactions between PTPRR and MAPK1 HeLa cells were stained with anti-PTPRR rabbit purified polyclonal 1:1200 and anti-MAPK1 mouse monoclonal antibody 1:50. Signals were detected by Duolink® 30 Detection Kit 613(red), and nuclei were counterstained with DAPI (blue). Each red dot represents the detection of protein-protein interaction complex. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

PTPRR antibody

Formalin-fixed and paraffin-embedded human brain tissue reacted with PTPRR polyclonal antibody ( Cat # PAB4084 ) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Hu E, P, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

PTPRR antibody

Human Placenta; WB Suggested Anti-PTPRR Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: Human Placenta; PTPRR antibody - N-terminal region (ARP45385_P050) in Human Placenta cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Chk, Hu, Ms, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

PTPRR antibody

PTPRR Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

PTPRR antibody

Human Jurkat; WB Suggested Anti-PTPRR Antibody Titration: 0.2-1 ug/ml. Positive Control: Jurkat cell lysate; PTPRR antibody - C-terminal region (ARP45387_P050) in Human Jurkat cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Can, Chk, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

PTPRR antibody

Immunohistochemistry-Paraffin: PCPTP1 Antibody [NBP1-84912] - Immunohistochemical staining of human colon shows moderate cytoplasmic positivity in glandular cells. Rabbit IgG Aff - Purified Hu ICC/IF, P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PTPRR (transcript variant 2)

PTPRR Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

PTPRR (transcript variant 1)

PTPRR Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

PTPRR

PTPRR Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

PTPRR

PTPRR Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

PTPRR 293T Cell Transient Overexpression Lysate(Denatured)

PTPRR 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

PTPRR overexpression lysate

PTPRR overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

PTPRR overexpression lysate

PTPRR overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

18 Item(s)

per page
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