Alternative names for PYX antibody
Transient receptor potential channel pyrexia
Frozen Sections (C), Paraffin Sections (P), Western blot / Immunoblot (WB)
Background of PYX antibody
FUNCTION: Receptor-activated non-selective cation channel involved in protection or tolerance from high temperature stress. Activated by temperatures above 40 degrees Celsius. More permeable to K(+) than to Na(+). May act in stress protection allow flies to survive in natural environments.; SUBUNIT: Homooligomer; between isoform A and isoform B. SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein. TISSUE SPECIFICITY: Expressed in various peripheral nerves and the central nerves in embryos. In adults, it is expressed in sensory neurons lying beneath the bristles around eyes, neurons innervating the bristles on the back of thorax and neurons in maxillary palps, proboscis and antennae. Expressed in multidendritic neurons, which mediate temperature sensing, as well as non-multidendritic neurons in larval epidermis. Localizes ubiquitously throughout neurites.