RAB27A / RAB27 antibody

Principal name

RAB27A / RAB27 antibody

Alternative names for RAB27A / RAB27 antibody

RAB-27, Ras-related protein Rab-27A, GTP-binding protein Ram

SwissProt ID

P23640 (Rat), P51159 (Human), Q1HE58 (Canfa), Q4LE85 (Pig), Q9ERI2 (Mouse)

Gene ID

5873 (RAB27A)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Can (Canine), Mky (Monkey)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C), Flow Cytometry (F), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP)

Background of RAB27A / RAB27 antibody

Ras-related protein (RAB27A), a member of the Ras family, is a GTP-binding protein that is involved in protein transport and small GTPase mediated signal transduction (1). RAB27A plays a role in cytotoxic granule exocytosis in lymphocytes (1). This process is mediated by RAB27A acting as an effector for JFC1/Slp1 and Munc13-4 (2). RAB27A also interacts with Slp4-a (synaptotagmin-like protein4-a) to negatively control dense-core vesicle exocytosis (3). In addition, it is required for granule maturation, granule docking, and priming at the immunologic synapse (1). RAB27A is more restricted in expression than other Ras members; it is highly expressed only in melanocytes, hematopoietic cells, and other secretory cells (4). Defects in RAB27A are a cause of Griscelli syndrome type 2 (GS2), which results in an uncontrolled T-lymphocyte and macrophage activation syndrome (1).

General readings

Matias Ostrowsk., et al. (2010) Nature Cell Biology. 12: 19-30.Lilian Chiang., et al. (2011) Am J Physiol Cell Physiol. 301: 507–521.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

pan RAB27 (C-term) antibody

pan RAB27 Goat IgG Aff - Purified Can, Hu, Mky, Ms, Rt C, ICC/IF, P, WB
20 µl / €50.00
  SICGEN

pan RAB27 (C-term) antibody

pan RAB27 Goat IgG Aff - Purified Can, Hu, Mky, Ms, Rt C, ICC/IF, P, WB
0.6 mg / €300.00
  SICGEN

pan RAB27 (C-term) antibody

pan RAB27 Goat IgG Aff - Purified Can, Hu, Mky, Ms, Rt C, ICC/IF, P, WB
1.5 mg / €450.00
  SICGEN

RAB27A / RAB27 antibody

Immunoperoxidase of monoclonal antibody to RAB27A on formalin-fixed paraffin-embedded human lymphoma. [antibody concentration 3 ug/ml] Mouse IgG1 1G7 Purified Hu E, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

RAB27A / RAB27 (C-term) antibody

RAB27A / RAB27 Goat IgG Aff - Purified Can, Hu, Mky, Ms, Rt C, ICC/IF, P, WB
0.2 mg / €320.00
  SICGEN

RAB27A / RAB27 (C-term) antibody

RAB27A / RAB27 Goat IgG Aff - Purified Can, Hu, Mky, Ms, Rt C, ICC/IF, P, WB
0.5 mg / €450.00
  SICGEN

RAB27A / RAB27 (C-term) antibody

RAB27A / RAB27 Goat IgG Aff - Purified Can, Hu, Mky, Ms, Rt C, ICC/IF, P, WB
20 µl / €50.00
  SICGEN

RAB27A / RAB27 (C-term) antibody

RAB27A / RAB27 Goat IgG Aff - Purified Can, Hu, Mky, Ms, Rt C, ICC/IF, P, WB
0.4 mg / €320.00
  SICGEN

RAB27A / RAB27 antibody

Western blot analysis of extracts of various cell lines, using RAB27A antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

RAB27A / RAB27 antibody

WB Suggested Anti-RAB27A Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: Human Stomach Rabbit IgG Purified Hu, Ms WB
50 µg / €325.00
  OriGene Technologies, Inc.

RAB27A / RAB27 antibody

The Cell lysates (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human RAB27A antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

Lane 1. : THP-1 cell lysate 
Lane 2. : A549 cell lysate Mouse IgG1 AT2E2 Purified Hu E, F, WB
0.1 ml / €310.00
  Acris Antibodies GmbH

RAB27A / RAB27 antibody

The Cell lysates (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human RAB27A antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

Lane 1. : THP-1 cell lysate 
Lane 2. : A549 cell lysate Mouse IgG1 AT2E2 Purified Hu E, F, WB
50 µl / €220.00
  Acris Antibodies GmbH

RAB27A / RAB27 antibody

RAB27A monoclonal antibody (M01), clone 4C1. Western Blot analysis of RAB27A expression in HL-60 ( Cat # L014V1 ). Mouse IgG1 4C1 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

RAB27A / RAB27 antibody

Human Stomach; WB Suggested Anti-RAB27A Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: Human Stomach; RAB27A antibody - middle region (ARP56591_P050) in Human Stomach cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

RAB27A / RAB27 antibody

RAB27A / RAB27 Rabbit Purified Hu, Ms, Rt C, P, WB
0.1 ml / €400.00
  Novus Biologicals Inc.

RAB27A / RAB27 antibody

Immunohistochemistry-Paraffin: RAB27A Antibody [NBP1-83327] - Immunohistochemical staining of human stomach shows strong cytoplasmic positivity in glandular cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

RAB27A / RAB27 antibody

Immunohistochemistry-Paraffin: RAB27A Antibody (EPR3021) [NBP1-95303] human tonsil tissue using anti- RAB27A. Rabbit EPR3021 Purified Hu, Rt F, ICC/IF, IP, P, WB
0.1 ml / €420.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

RAB27A / RAB27 (transcript variant 2)

RAB27A / RAB27 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

RAB27A / RAB27 (transcript variant 3)

RAB27A / RAB27 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

RAB27A / RAB27 (transcript variant 1)

RAB27A / RAB27 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

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