RAB3A antibody

Principal name

RAB3A antibody

Alternative names for RAB3A antibody

Rab-3A, Ras-related protein Rab-3A

SwissProt ID

P11023 (Bovin), P20336 (Human), P63011 (Mouse), P63012 (Rat), Q06AU3 (Pig)

Gene ID

5864 (RAB3A), 25531 (Rab3a)

Available reactivities

Can (Canine), Hst (Hamster), Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Por (Porcine), African clawed frog, Mky (Monkey), Xen (Xenopus)

Available hosts

Rabbit, Mouse, Goat

Available applications

Immunoprecipitation (IP), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Frozen Sections (C)

Background of RAB3A antibody

Rab proteins are low-molecular-weight GTP-binding proteins that form the largest branch of the Ras superfamily of GTPases. Located on the cytoplasmic face of organelles and vesicles, rab proteins are involved in intracellular membrane fusion reactions. Three membrane proteins, synaptosomal associated protein of 25 kDa (SNAP-25), synaptobrevin, and syntaxin, form the core of a ubiquitous membrane fusion machine that interacts with the soluble proteins N-ethylmaleimide-sensitive factor (NSF) and a-SNAP. Rab proteins, in coordination with the core fusion machinery and Munc-18, help to mediate vesicle docking and fusion. There exist over 40 rab proteins that have been described in mammals and the best studied is rab 3A. Rab 3A is found to be abundant in presynaptic nerve terminals and is also found to be crucial in acrosomal exocytosis in human spermatozoa. Abnormal accumulation of rab 3A in the cytoplasm of Purkinje cells has been reported in the prion protein related Creutzfeldt-Jakob disease.

General readings

Schluter OM, Schmitz F, Jahn R, Rosenmund C, Sudhof TC (2004) A Complete Genetic Analysis of Neuronal Rab3 Function. J Neuroscience 24(29):6629-6637Schluter OM, Basu J, Sudhof TC, Rosenmund C (2006) Rab3 Superprimes Synaptic Vesicles for Release: Implications for Short-term Synaptic Plasticity. J Neuroscience 26(4):1239-1246.Coppola T, Perret-Menoud V, Gattesco S, Magnin S, Pombo I, Blank U, Regazzi R (2002) The death domain of Rab3 guanine nucleotide exchange protein in GDP/GTP exchange activity in living cells. J Biochem 362 (Pt.2):273-9.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

RAB3 (N-term) antibody

Western blot of rat cortex lysate showing specific labeling of the ~27k Rab3 protein. Rabbit IgG Aff - Purified Hu, Ms, non-Human Primates, Rt, Xen WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

RAB3 Pan (C-term) antibody

RAB3 Goat IgG Aff - Purified Can, Hu, Mky, Ms, Rt C, ICC/IF, P, WB
20 µl / €50.00
  SICGEN

RAB3 Pan (C-term) antibody

RAB3 Goat IgG Aff - Purified Can, Hu, Mky, Ms, Rt C, ICC/IF, P, WB
0.6 mg / €320.00
  SICGEN

RAB3 antibody

RAB3 Rabbit IgG Purified Hu, Mky, Ms, Rt, Xen WB
0.1 ml / €510.00
  Acris Antibodies GmbH

RAB3 antibody

Western blot of rat cortex lysate showing specific labeling of the ~27k RAB3 protein. Using RAB3 polyclonal antibody ( Cat # PAB9627 ). Rabbit IgG Hu, Ms, Rt
0.1 ml / €470.00
  Abnova Taiwan Corp.

RAB3A antibody

RAB3A antibody - C-terminal region validated by WB using Fetal Brain at 1.25 ug/ml. Rabbit IgG Purified Hu, Mky WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

RAB3A (202-217) antibody

Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with RAB3A antibody AP22765PU-N at 10 µg/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Rabbit Aff - Purified Bear, Bov, Bt, Can, Elephant, Eq, Hst, Hu, Mky, Ms, Op, Platypus, Por, Prim, Rt, Xen P, WB
50 µg / €470.00
  Acris Antibodies GmbH

RAB3A (N-term) antibody

Western blot analysis of RAB3A Antibody (N-term) Cat.-No AP53542PU-N in Y79 cell line lysates (35ug/lane). This demonstrates the RAB3A antibody detected the RAB3A protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

RAB3A antibody

RAB3A Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

RAB3A antibody

RAB3A Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

RAB3A antibody

RAB3A Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

RAB3A antibody

Immunofluorescence of monoclonal antibody to RAB3A on HeLa cell. [antibody concentration 25 ug/ml] Mouse IgG1 4H7 Purified Hu E, ICC/IF, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

RAB3A antibody

Human Fetal Brain; RAB3A antibody - C-terminal region (AVARP13056_T100) validated by WB using Fetal Brain at 1.25ug/ml.; RAB3A antibody - C-terminal region (AVARP13056_T100) in Human Fetal Brain cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Can, Hu, Ms, Por, Rt
0.1 mg / €310.00
  AVIVA Systems Biology

RAB3A antibody

Western Blot: Rab3A Antibody [NB120-3335] - Figure 1 shows a Western blot of rab 3A on Hepa1 cell lysate using NB120-3335. Rabbit IgG Serum Can, Hu, Ms, Rt IP, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

RAB3A antibody

Western Blot: Rab3A Antibody [NB300-734] - Rat cortex lysate showing specific labeling of the ~27k Rab3 protein. Rabbit Aff - Purified Rt WB
0.1 ml / €380.00
  Novus Biologicals Inc.

RAB3A antibody

Immunohistochemistry-Paraffin: Rab3A Antibody [NBP1-89470] - Immunohistochemical staining of human cerebral cortex shows distinct positivity in neuropil. Rabbit IgG Aff - Purified Hu ICC/IF, P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

RAB3A

RAB3A Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

RAB3A (1-220, His-tag)

RAB3A Human Purified > 90 % E. coli
0.25 mg / €750.00
  Acris Antibodies GmbH

RAB3A (1-220, His-tag)

RAB3A Human Purified > 90 % E. coli
50 µg / €300.00
  Acris Antibodies GmbH

RAB3A

RAB3A Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

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