RAB8A antibody

Principal name

RAB8A antibody

Alternative names for RAB8A antibody

RAB8, MEL, Ras-related protein Rab-8A, Oncogene c-mel

SwissProt ID

A4FV54 (Bovin), P35280 (Rat), P55258 (Mouse), P61006 (Human), P61007 (Canfa), Q5F470 (Chick)

Gene ID

4218 (RAB8A), 17274 (Rab8a), 117103

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Ms (Mouse), Rt (Rat), Ze (Zebrafish), African clawed frog, Mky (Monkey)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of RAB8A antibody

RAB8A is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. The putative effector-binding site of this protein is similar to that of the RAB/YPT proteins. However, this protein contains a C-terminal CAAX motif that is characteristic of many RAS superfamily members but which is not found in YPT1 and the majority of RAB proteins. Although this gene was isolated as a transforming gene from a melanoma cell line, no linkage between MEL and malignant melanoma has been demonstrable.The protein encoded by this gene is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. This protein shares 97%, 96%, and 51% similarity with the dog RAB8, mouse MEL, and mouse YPT1 proteins, respectively and contains the 4 GTP/GDP-binding sites that are present in all the RAS proteins. The putative effector-binding site of this protein is similar to that of the RAB/YPT proteins. However, this protein contains a C-terminal CAAX motif that is characteristic of many RAS superfamily members but which is not found in YPT1 and the majority of RAB proteins. Although this gene was isolated as a transforming gene from a melanoma cell line, no linkage between MEL and malignant melanoma has been demonstrable. This oncogene is located 800 kb distal to MY09B on chromosome 19p13.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

Yoshimura S, Egerer J, Fuchs E, Haas AK, Barr FA.
Functional dissection of Rab GTPases involved in primary cilium formation.
J Cell Biol. 2007 Jul 30;178(3):363-9. Epub 2007 Jul 23.
PMID: 17646400

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

pan RAB8 (C-term) antibody

pan RAB8 Goat IgG Aff - Purified Can, Hu, Mky, Ms, Rt C, ICC/IF, P, WB
0.6 mg / €300.00
  SICGEN

RAB8A (C-term) antibody

  Goat Polyclonal Antibody against RAB8A  
TA303328 (0.1µg/ml) staining of Human Brain (Cerebellum) lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Bov, Can, Hu
0.1 mg / €325.00
  OriGene Technologies, Inc.

RAB8A antibody

  Anti-RAB8A Rabbit Polyclonal Antibody  
Gel: 10%SDS-PAGE,Lysate: 40 µg,Lane 1-2: Human liver cancer tissue, Hela cells,Primary antibody: RAB8A Antibody at dilution 1/100 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 2 minutes Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

RAB8A antibody

  Rabbit Polyclonal Anti-RAB8A Antibody  
RAB8A antibody - middle region validated by WB using 1. Human Cervical Cancer Cell Lysate (15ug); 2. Monkey Fibroblast Cell Lysate (15ug); 3. Human Cervical Cancer Cell transfected with mouse Rab8A-GFP (15ug) at 1:1000. Rabbit IgG Purified Hu, Mky WB
50 µg / €325.00
  OriGene Technologies, Inc.

RAB8A antibody

  Rabbit Polyclonal Anti-RAB8A Antibody  
Gel: 6%SDS-PAGE,Lysate: 40 ug,,Primary antibody: (RAB8A Antibody) at dilution 1/200 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 40 seconds Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

RAB8A

  Recombinant protein of human RAB8A, member RAS oncogene family (RAB8A)  
RAB8A Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Rab8a (GFP-tagged) - Mouse RAB8A, member RAS oncogene family (Rab8a), 200 uL, >10^7 TU/mL

Lenti ORF particles, Rab8a (GFP-tagged) - Mouse RAB8A, member RAS oncogene family (Rab8a), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Rab8a (Myc-DDK-tagged) - Mouse RAB8A, member RAS oncogene family (Rab8a), 200 uL, >10^7 TU/mL

Lenti ORF particles, Rab8a (Myc-DDK-tagged) - Mouse RAB8A, member RAS oncogene family (Rab8a), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Rab8a (GFP-tagged ORF) - Rat RAB8A, member RAS oncogene family (Rab8a), 200 uL, >10^7 TU/mL

Lenti ORF particles, Rab8a (GFP-tagged ORF) - Rat RAB8A, member RAS oncogene family (Rab8a), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Rab8a (Myc-DDK-tagged ORF) - Rat RAB8A, member RAS oncogene family (Rab8a), 200 uL, >10^7 TU/mL

Lenti ORF particles, Rab8a (Myc-DDK-tagged ORF) - Rat RAB8A, member RAS oncogene family (Rab8a), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

10 Item(s)

per page
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