RAC2 antibody

Principal name

RAC2 antibody

Alternative names for RAC2 antibody

p21-Rac2, Ras-related C3 botulinum toxin substrate 2, Small G protein

SwissProt ID

O88931 (Cavpo), P15153 (Human), Q05144 (Mouse), Q9TU25 (Bovin)

Gene ID

5880 (RAC2), 19354 (Rac2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Goat, Rabbit

Available applications

Flow Cytometry (F), Immunocytochemistry/Immunofluorescence (ICC/IF), Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C)

Background of RAC2 antibody

Rac and Cdc42 are members of the Rho-GTPase family. In mammals, Rac exists as three isoforms, Rac1, Rac2 and Rac3, which are highly similar in sequence. Rac1 and Cdc42, the most widely studied of this group, are ubiquitously expressed. Rac2 is expressed in cells of hematopoietic origin, and Rac3, while highly expressed in brain, is also found in many other tissues. Rac and Cdc42 play key sigling roles in cytoskeletal reorganization, membrane trafficking, transcriptiol regulation, cell growth and development. GTP binding stimulates the activity of Rac/Cdc42, and the hydrolysis of GTP to GDP through the protein's intrinsic GTPase activity, rendering it ictive. GTP hydrolysis is aided by GTPase activating proteins (GAPs), while exchange of GDP for GTP is facilitated by guanine nucleotide exchange factors (GEFs). Another level of regulation is achieved through the binding of RhoGDI, a guanine nucleotide dissociation inhibitor, which retains Rho family GTPases, including Rac and Cdc42, in their ictive GDP-bound state.

General readings

Reibel L, Dorseuil O, Stancou R, Bertoglio J, Gacon G.
A hemopoietic specific gene encoding a small GTP binding protein is overexpressed during T cell activation.
Biochem Biophys Res Commun. 1991 Mar 15;175(2):451-8.
PMID: 1902092

19 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

RAC2 (C-term) antibody

  Goat Polyclonal Antibody against RAC2  
TA302763 staining (2µg/ml) of MOLT-4 lysate (RIPA buffer, 35µg total protein per lane).  Primary incubated for 1 hour.  Detected by western blot using chemiluminescence. Goat Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

RAC2 antibody

  Anti-RAC2 Rabbit Polyclonal Antibody  
Predicted band size: 21 kDa . Positive control: Jurkat and HL-60 cell lysate. Recommended dilution: 1/500-2000. (Gel: 10%SDS-PAGE Lane1: Jurkat cell lysate Lane2: HL-60 cell lysate Lysates: 40 ug per lane Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

RAC2 antibody

  Goat Polyclonal RAC2 Antibody  
Western Blot: RAC2 Antibody [TA337190] - Analysis of RAC2 in Human Tonsil lysate (RIPA buffer, 35ug total protein per lane) using at 0.3ug/ml. Primary incubated for 1 hour. Detected by western blot using chemiluminescence. Goat Purified Hu, Ms C, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

RAC2 (1-189) antibody

ICC/IF analysis of RAC2 in Jurkat cells line, stained with DAPI (Blue) for nucleus staining and monoclonal anti human RAC2 antibody (1: 100) with goat anti mouse IgG - Alexa fluor 488 conjugate (Green). Mouse IgG2b AT2G11 Purified Hu E, F, ICC/IF, WB
0.1 ml / €310.00
  Acris Antibodies GmbH

RAC2 (1-189) antibody

ICC/IF analysis of RAC2 in Jurkat cells line, stained with DAPI (Blue) for nucleus staining and monoclonal anti human RAC2 antibody (1: 100) with goat anti mouse IgG - Alexa fluor 488 conjugate (Green). Mouse IgG2b AT2G11 Purified Hu E, F, ICC/IF, WB
50 µl / €230.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

RAC2 - human gene knockout kit via CRISPR

RAC2 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

RAC2 - human gene knockout kit via CRISPR

RAC2 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

RAC2 - human gene knockout kit via CRISPR

RAC2 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

RAC2 - human gene knockout kit via CRISPR

RAC2 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Rac2 - mouse gene knockout kit via CRISPR

Rac2 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Rac2 - mouse gene knockout kit via CRISPR

Rac2 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Rac2 - mouse gene knockout kit via CRISPR

Rac2 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Rac2 - mouse gene knockout kit via CRISPR

Rac2 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

RAC2 (1-189, His-tag)

RAC2 Human Purified > 95 % by SDS - PAGE E. coli
0.5 mg / €750.00
  Acris Antibodies GmbH

RAC2 (1-189, His-tag)

RAC2 Human Purified > 95 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, RAC2 (mGFP-tagged)-Human ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) (RAC2), 200 uL, >10^7 TU/mL

Lenti ORF particles, RAC2 (mGFP-tagged)-Human ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) (RAC2), 200 uL, >10^7 TU/mL  
200 µl / €990.00
  OriGene Technologies, Inc.

Lenti ORF particles, RAC2 (Myc-DDK-tagged)-Human ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) (RAC2), 200 uL, >10^7 TU/mL

Lenti ORF particles, RAC2 (Myc-DDK-tagged)-Human ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) (RAC2), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Rac2 (GFP-tagged) - Mouse RAS-related C3 botulinum substrate 2 (Rac2), 200 uL, >10^7 TU/mL

Lenti ORF particles, Rac2 (GFP-tagged) - Mouse RAS-related C3 botulinum substrate 2 (Rac2), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Rac2 (Myc-DDK-tagged) - Mouse RAS-related C3 botulinum substrate 2 (Rac2), 200 uL, >10^7 TU/mL

Lenti ORF particles, Rac2 (Myc-DDK-tagged) - Mouse RAS-related C3 botulinum substrate 2 (Rac2), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

19 Item(s)

per page
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