RANBP10 antibody

Principal name

RANBP10 antibody

Alternative names for RANBP10 antibody

Ran-binding protein 10, KIAA1464

SwissProt ID

A3KMV8 (Bovin), Q1LUS8 (Danre), Q6VN19 (Mouse), Q6VN20 (Human)

Gene ID

57610 (RANBP10), 74334 (Ranbp10)

Available reactivities

Hu (Human)

Available hosts

Rabbit

Available applications

Paraffin Sections (P), Enzyme Immunoassay (E), Western blot / Immunoblot (WB)

Background of RANBP10 antibody

The RAN binding protein 10 (RANBP10) is a cytoplasmic guanine nucleotide exchange factor that shares high sequence similarity to the MET-interacting protein RANBP9. RANBP10 is expressed in the cytoplasm of mature megakaryocytes (MKs) and platelets where it localizes to polymerized noncentrosomal microtubules. RANBP10 possesses guanine nucleotide exchange factor activity towards RAN, a GTPase involved in nucleocytoplasmic traffic, spindle formation at mitosis, and nuclear envelope assembly during telophase, suggesting that RANBP10 may also be involved in these activities. RANBP10 depletion in vitro caused the disturbance of polymerized filaments in MKs and platelets in RANBP10-null mice exhibited disorders in microtubule filament numbers and localization, indicating that RANBP10 may play a significant role in maintaining microtubule dynamics.

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CRISPR

Catalog No. Species Donor Vector  

RANBP10 - human gene knockout kit via CRISPR

RANBP10 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Ranbp10 - mouse gene knockout kit via CRISPR

Ranbp10 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

2 Item(s)

per page
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