RANBP10 antibody
Principal name
RANBP10 antibody
Alternative names for RANBP10 antibody
Ran-binding protein 10, KIAA1464
Ncbi ID
9606, NP_065901.1, NM_020850, NP_065901, EAW83167, NP_665823.2, BC024698, NM_145824
Available reactivities
Available hosts
Available applications
Paraffin Sections (P), Enzyme Immunoassay (E), Western blot / Immunoblot (WB)
Background of RANBP10 antibody
The RAN binding protein 10 (RANBP10) is a cytoplasmic guanine nucleotide exchange factor that shares high sequence similarity to the MET-interacting protein RANBP9. RANBP10 is expressed in the cytoplasm of mature megakaryocytes (MKs) and platelets where it localizes to polymerized noncentrosomal microtubules. RANBP10 possesses guanine nucleotide exchange factor activity towards RAN, a GTPase involved in nucleocytoplasmic traffic, spindle formation at mitosis, and nuclear envelope assembly during telophase, suggesting that RANBP10 may also be involved in these activities. RANBP10 depletion in vitro caused the disturbance of polymerized filaments in MKs and platelets in RANBP10-null mice exhibited disorders in microtubule filament numbers and localization, indicating that RANBP10 may play a significant role in maintaining microtubule dynamics.
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| TA306949 | RANBP10 antibody |
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| Rabbit Polyclonal RANBP10 Antibody | |||||||
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Rabbit | IgG | Aff - Purified | Hu | E, P, WB |
0.1 mg /
€415.00
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| OriGene Technologies, Inc. | |||||||
 +2 additional images |
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