RanBP11 / Importin-11 antibody

Principal name

RanBP11 / Importin-11 antibody

Alternative names for RanBP11 / Importin-11 antibody

Imp11, IPO11, Ran-binding protein 11

SwissProt ID

Q8K2V6 (Mouse), Q9UI26 (Human)

Gene ID

51194 (IPO11)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Mky (Monkey), Chimp (Chimpanzee)

Available hosts

Rabbit

Available applications

Enzyme Immunoassay (E), Paraffin Sections (P), Western blot / Immunoblot (WB), Frozen Sections (C)

Background of RanBP11 / Importin-11 antibody

IPO11 functions in nuclear protein import as nuclear transport receptor. It serves as receptor for nuclear localization signals (NLS) in cargo substrates and is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP-and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity). It mediates the nuclear import of UBE2E3, and of RPL12 (By similarity).

General readings

Plafker,S.M. et.al., Mol. Cell. Biol. 22 (4), 1266-1275 (2002)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

RanBP11 / Importin-11 antibody

Host: Rabbit; Target Name: Ipo11; Sample Tissue: Rat Pancreas lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Hu, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

RanBP11 / Importin-11 (N-term) antibody

Western blot analysis of IPO11 Antibody (N-term) (AP18075PU-N) in Hela cell line lysates (35ug/lane). IPO11 (arrow) was detected using the purified Pab. Rabbit Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

RanBP11 / Importin-11 (C-term) antibody

Western blot analysis of RanBP11 / Importin-11 Antibody (C-term) Cat.-No AP52222PU-N in CEM cell line lysates (35ug/lane). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

RanBP11 / Importin-11 antibody

Western blot analysis of Importin-11 in HeLa lysate in the 1 ) absence and 2 ) presence of immunizing peptide. Using IPO11 polyclonal antibody ( Cat # PAB0291 ) at 1 µg/ml. Rabbit Bov, Chimp, Hu, Mky, Ms, Rt WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

RanBP11 / Importin-11 antibody

Western Blot: Importin-11 Antibody [NB100-56484] - Western blot analysis of Importin-11 in HeLa lysate in the 1) absence and 2) presence of immunizing peptide using NB 100-56484 at 1 ug/ml. Rabbit IgG Aff - Purified Bov, Can, Hu, Mky, Ms, Rt WB
0.1 mg / €320.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

RanBP11 / Importin-11 (transcript variant 2)

RanBP11 / Importin-11 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

IPO11 overexpression lysate

IPO11 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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