RanBP4 / Importin-4 antibody

Principal name

RanBP4 / Importin-4 antibody

Alternative names for RanBP4 / Importin-4 antibody

IMP4, IPO4, IMP4B, Importin-4b, Ran-binding protein 4

SwissProt ID

Q8TEX9 (Human), Q8VI75 (Mouse)

Gene ID

79711 (IPO4)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Rabbit

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Paraffin Sections (P), Western blot / Immunoblot (WB)

Background of RanBP4 / Importin-4 antibody

Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity). Mediates the nuclear import of RPS3A. In vitro, mediates the nuclear import of human cytomegalovirus UL84 by recognizing a non-classical NLS.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

RanBP4 / Importin-4 antibody

Host: Rabbit; Target Name: IPO4; Sample Tissue: Hela Whole Cell lysates; Antibody Dilution: 1.0ug/mlIPO4 is supported by BioGPS gene expression data to be expressed in HeLa Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

RanBP4 / Importin-4 antibody

Western Blot: Importin4 Antibody [NBP1-46165]-Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells.  Antibodies: Affinity purified rabbit anti-Importin 4 antibody used for IP at 10 mcg/mg lysate.  Importin 4 was also immunoprecipitated by rabbit anti-Importin 4 antibody NBP1-46166, which recognizes a downstream epitope. Rabbit Aff - Purified Hu IP, P
0.1 mg / €440.00
  Novus Biologicals Inc.

RanBP4 / Importin-4 antibody

Western Blot: Importin4 Antibody [NBP1-46166]-Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells.  Antibodies: Affinity purified rabbit anti-Importin 4 antibody used for IP at 10 mcg/mg lysate.  Importin 4 was also immunoprecipitated by rabbit anti-Importin 4 antibody NBP1-46165, which recognizes an upstream epitope. Rabbit Aff - Purified Hu IP, P
0.1 mg / €440.00
  Novus Biologicals Inc.

RanBP4 / Importin-4 antibody

Immunohistochemistry-Paraffin: Importin4 Antibody [NBP1-89841] Immunohistochemical staining of human colon shows strong cytoplasmic positivity in glandular cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

RanBP4 / Importin-4

RanBP4 / Importin-4 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

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