RanBP5 / Importin-5 antibody

Principal name

RanBP5 / Importin-5 antibody

Alternative names for RanBP5 / Importin-5 antibody

Importin subunit beta-3, Karyopherin beta-3, Ran-binding protein 5, KPNB3, IPO5

SwissProt ID

Q86XC7 (Human)

Gene ID

3843 (IPO5)

Ncbi ID

9606, NP_002262

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of RanBP5 / Importin-5 antibody

Nucleocytoplasmic transport takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Karyopherin (importin) beta 3 (KPNB3) is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism.

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