RanBP7 / Importin-7 antibody

Principal name

RanBP7 / Importin-7 antibody

Alternative names for RanBP7 / Importin-7 antibody

IMP7, Ran-binding protein 7, IPO7

SwissProt ID

O95373 (Human), Q9EPL8 (Mouse)

Gene ID

10527 (IPO7), 233726 (Ipo7)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Ms (Mouse), Rt (Rat)

Available hosts

Goat, Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of RanBP7 / Importin-7 antibody

The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization sigl. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. Similar to importin-beta, this protein prevents the activation of Ran's GTPase by RanGAP1 and inhibits nucleotide exchange on RanGTP, and also binds directly to nuclear pore complexes where it competes for binding sites with importin-beta and transportin. This protein has a Ran-dependent transport cycle and it can cross the nuclear envelope rapidly and in both directions. At least four importin beta-like transport receptors, mely importin beta itself, transportin, RanBP5 and RanBP7, directly bind and import ribosomal proteins. [provided by RefSeq]

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CRISPR

Catalog No. Species Donor Vector  

IPO7 - human gene knockout kit via CRISPR

IPO7 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Ipo7 - mouse gene knockout kit via CRISPR

Ipo7 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

2 Item(s)

per page
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