RAP2B antibody

Principal name

RAP2B antibody

Alternative names for RAP2B antibody

Rap-2b, Ras-related protein Rap-2b

SwissProt ID

P61225 (Human), P61226 (Mouse), P61227 (Rat)

Gene ID

5912 (RAP2B)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of RAP2B antibody

Rap2B is a 21 kDa small GTP-binding protein that that exhibits 46% identity with Ras proteins and is similarly post-translationally modified by farnesyl and palmitate groups. It colocalizes with several markers of the Golgi complex, thus indicating that its site of function was distinct from that of Rap1A. In contrast to Rap1A, Rap2B protein does not interfere with Ras-induced transformation suggesting that the activity of Rap proteins goes beyond the regulation of Ras protein function.
Ras proteins provide a crucial link in the intracellular signalling cascades. Ras proteins are members of the small G protein family. These proteins are characterized by a molecular weight between 20 and 30 kDa, the ability to bind GTP or GDP and a low intrinsic GTPase activity. These proteins relay signals from the plasma membrane activated by receptor tyrosine kinases to the nucleus via a network of serine/threonine kinases. Ras proteins belong to a family of approximately 40 mammalian and 60 non-mammalian proteins. Ras proteins were first discovered as the hyperactive products of mutant Ras genes which promote cancer by disrupting the normal controls on cell proliferation and differentiation; about 30% of human cancers have mutations in a Ras gene.

General readings

Evellin. S., et al. (2002) J Biol Chem 277: 16805-16813Stope. M.B., et al. (2004) Mol Cell Biol 24: 4664-4676 Greco. F., et al. (2006) Biochim Biophys Acta 1763: 330-335

13 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

RAP2B antibody

Western blot analysis of extracts from K562 cells, using RAP2B antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

RAP2B antibody

The cell lysates of PC3 (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human RAP2B antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Mouse IgG1 AT62D9 Purified Hu E, WB
0.1 ml / €310.00
  Acris Antibodies GmbH

RAP2B antibody

The cell lysates of PC3 (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human RAP2B antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Mouse IgG1 AT62D9 Purified Hu E, WB
50 µl / €220.00
  Acris Antibodies GmbH

RAP2B antibody

RAP2B Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

RAP2B antibody

Immunoperoxidase of monoclonal antibody to RAP2B on formalin-fixed paraffin-embedded human malignant lymphoma, diffuse large B tissue. [antibody concentration 1ug/ml] Mouse IgG2b 4F12-3C6 Purified Hu E, ICC/IF, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

RAP2B antibody

RAP2B Mouse IgG M1 Ascites Hu E, WB
0.2 ml / €370.00
  Abnova Taiwan Corp.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

RAP2B

RAP2B Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

RAP2B

RAP2B Human Purified
25 µg / €400.00
  Acris Antibodies GmbH

RAP2B (1-183, His-tag)

RAP2B Human Purified > 95 % by SDS - PAGE E. coli
0.5 mg / €730.00
  Acris Antibodies GmbH

RAP2B (1-183, His-tag)

RAP2B Human Purified > 95 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

RAP2B

RAP2B Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

RAP2B

RAP2B Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

RAP2B overexpression lysate

RAP2B overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

13 Item(s)

per page
  • LinkedIn