RASA2 antibody

Principal name

RASA2 antibody

Alternative names for RASA2 antibody

Ras GTPase-activating protein 2, GAP1M, RASGAP

SwissProt ID

P58069 (Mouse), Q15283 (Human), Q63713 (Rat)

Gene ID

5922 (RASA2)

Available reactivities

Bov (Bovine), Hst (Hamster), Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of RASA2 antibody

The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member has a perinuclear localization and is an inositol 1,3,4,5-tetrakisphosphate-binding protein; a compound suggested to function as a second messenger. [provided by RefSeq, Jul 2008].

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