Rat IgM antibody

Principal name

Rat IgM antibody

Alternative names for Rat IgM antibody

Rat Immunoglobulin M

Available reactivities

Rt (Rat)

Available hosts

Rabbit, Goat, Mouse

Available applications

Enzyme Immunoassay (E), Flow Cytometry (F), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Functional assay (FN), Paraffin Sections (P), Frozen Sections (C)

Background of Rat IgM antibody

IgM normally constitutes about 10% of serum immunoglobulins. IgM antibody is prominent in early immune responses to most antigens and predominates in certain antibody responses such as 'natural' blood group antibodies. IgM (with IgD) is the major immunoglobulin expressed on the surface of B cells. The gene for the mu constant region contains four domains separated by short intervening sequences.
Class specific anti immunoglobulin antibodies are useful for: The characterization of malignant B cell proliferations. All but acute lymphocytic leukemias share either surface or intra cytoplasmic Ig with an isotypic restriction, which suggest the monoclonal nature of the cell population. Most of the chronic lymphocytic leukemias, non Hodgkin lymphomas and Burkitt's lymphoma bear surface IgM, whereas plasmocytes from Waldenström's disease bear intracytoplasmic IgM. The other isotypes are less frequently found. On the other hand multiple myelomas are usually of the IgG or IgA type.
Characterization of plasma cells in inflammatory conditions: Plasma cell typing can be of use for the classification of intestinal inflammatory conditions such as inflammatory bowel disease and allergic conditions. In the latter a specific increase in the number of IgE plasma cells can be demonstrated.

Items 1 to 20 of 29 total

per page
Page:
  1. 1
  2. 2

Secondary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Rat IgM (Mu chain specific)

Rat IgM Mouse IgG1 Biotin Rt E, F, ICC/IF
0.5 mg / €310.00
  Acris Antibodies GmbH

Rat IgM (Mu chain specific)

Rat IgM Mouse IgG1 M 2A1 Cy5 Rt F, ICC/IF
0.1 mg / €410.00
  Acris Antibodies GmbH

Rat IgM (Mu chain specific)

Rat IgM Mouse IgG1 M 2A1 FITC Rt F, ICC/IF
0.5 mg / €330.00
  Acris Antibodies GmbH

Rat IgM (Mu chain specific)

Rat IgM Mouse IgG1 M 2A1 HRP Rt E
1 ml / €400.00
  Acris Antibodies GmbH

Rat IgM (Mu chain specific)

Rat IgM Mouse IgG1 M 2A1 Purified E, F, ICC/IF
0.5 mg / €280.00
  Acris Antibodies GmbH

Rat IgM (Mu chain specific)

Immunofluorescent Staining: BALB/c splenocytes were incubated with Rat IgM Isotype Control, Rat anti-Mouse CD22 (2D6, Rat IgG1), Rat anti-Mouse CD8 (53-6.7, Rat IgG2a), Rat anti-Mouse CD45 (LCA) (I3/2.3, Rat IgG2b), Rat anti-Mouse CD3(C363.29B, Rat IgG2c), and Rat anti-Mouse CD45RC (GL24, rat IgM). After washing, the cells were stained with PE-labeled Mouse Anti-Rat IgM. Small Lymphocytes were gated and analyzed on a FACScan(TM) flow cytometer (BDIS, San Jose, CA). Amount Used: < / = 0.02 µg/10e6 cells. Mouse IgG1 M 2A1 PE Rt F, ICC/IF
0.1 mg / €320.00
  Acris Antibodies GmbH

Rat IgM Mu chain specific F(ab’)2 Fragment

Rat IgM Mouse IgG1 M 2A1 Low Endotoxin Rt FN
0.5 mg / €410.00
  Acris Antibodies GmbH

Rat IgM Mu chain specific F(ab’)2 Fragment

B Cell Stimulation: 5 x 10e5 SD Rat splenocytes were incubated with the indicated concentrations of purified Mouse F(ab')2 Anti-Rat IgM, clone M2A1, for 48 hours. B cell proliferation was determined by 3H-thymidine
incorporation assay. Amount Used: < / = 10 μg/mL Mouse IgG1 M 2A1 Purified Rt FN
0.5 mg / €360.00
  Acris Antibodies GmbH

Rat IgM (Mu chain specific)

Rat IgM Mouse IgG1 HIS40 Supernatant Rt C, ICC/IF
1 ml / €240.00
  Acris Antibodies GmbH

Rat IgM

Rat IgM Goat IgG Rt E, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

Rat IgM

Rat IgM Goat IgG FITC Rt F
0.5 mg / €410.00
  Acris Antibodies GmbH

Rat IgM

Rat IgM Goat IgG HRP Rt E, WB
0.5 mg / €330.00
  Acris Antibodies GmbH

Rat IgM

Rat IgM Goat IgG Purified Rt E, F, WB
0.5 mg / €310.00
  Acris Antibodies GmbH

Rat IgM (Mu chain specific)

Rat IgM Rabbit AP
1 mg / €340.00
  Acris Antibodies GmbH

Rat IgM (Mu chain specific)

Rat IgM Rabbit Biotin
1.5 mg / €290.00
  Acris Antibodies GmbH

Rat IgM (Mu chain specific)

Rat IgM Rabbit FITC
1.5 mg / €240.00
  Acris Antibodies GmbH

Rat IgM (Mu chain specific)

Rat IgM Rabbit HRP
1.5 mg / €310.00
  Acris Antibodies GmbH

Rat IgM (Mu chain specific)

Rat IgM Rabbit Aff - Purified
2 mg / €240.00
  Acris Antibodies GmbH

Rat IgM (Mu chain specific)

Rat IgM Rabbit TRITC
1.5 mg / €240.00
  Acris Antibodies GmbH

Rat IgM (Mu chain specific)

Rat IgM Rabbit Texas Red
1.5 mg / €290.00
  Acris Antibodies GmbH

Items 1 to 20 of 29 total

per page
Page:
  1. 1
  2. 2
  • LinkedIn