RBBP2H1 / JARID1B antibody

Principal name

RBBP2H1 / JARID1B antibody

Alternative names for RBBP2H1 / JARID1B antibody

PLU-1, PLU1, Retinoblastoma-binding protein 2 homolog 1, CT31, Histone demethylase JARID1B, Jumonji/ARID domain-containing protein 1B

SwissProt ID

Q5F3R2 (Chick), Q80Y84 (Mouse), Q9UGL1 (Human)

Gene ID

10765 (KDM5B), 51780 (KDM3B), 75605 (Kdm5b)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Dros (Drosophila), Ms (Mouse), Rt (Rat), African clawed frog

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of RBBP2H1 / JARID1B antibody

Jumonji AT-rich interactive domain 1B (JARID1B) also known as Jumonji/ARID domain-containing protein 1B, Lysine-specific demethylase 5B (KDM5B), Cancer/testis antigen 31 (CT31), Histone demethylase JARID1B, PLU-1, and Retinoblastoma-binding protein 2 homolog 1 (RBP2-H1), is a member of the JARID 1 family. The JARID 1 proteins (JARID1A, JARID1B, JARID1C and JARID1D) catalyze the demethylation of histones on lysine, and JARID1B specifically demethylates lysine 4 on Histone H3. JARID1B functions as a transcriptiol co-repressor for FOXG1B and PAX9. In addition, JARID1B may play a considerable role in cancer research as it assists in the propagation of breast cancer cells by repressing the tumor suppressor genes BRCA1 and HOXA5. Conversely, JARID1B acts as a direct suppressor of melanoma. As result, the JARID1B protein is up regulated in breast cancer and down regulated in melanoma and glioblastomas. In general, JARID1B expression is ubiquitous; with the highest expression seen in testis. JARID1B is subject to post translatiol phosphorylation and has two known isoforms; isoform 1: 175.6kDa and isoform 2: 179.4kDa.

General readings

Hu,Z., (2001) Oncogene 20 (47), 6946-6954

13 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

RBBP2H1 / JARID1B antibody

Immunohistochemistry: JARID1B Antibody [TA336866] - IHC analysis of JARID1B in human breast cancer xenograft using DAB with hematoxylin counterstain. Rabbit Purified Hu C, ICC/IF, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

RBBP2H1 / JARID1B antibody

WB was performed on whole cell lysates from mouse fibroblasts (NIH3T3) and embryonic stem cells (E14Tg2a) with the antibody against mouse Jarid1b, diluted 1:500 in BSA/PBS-Tween. The molecular weight marker (in kDa) is shown on the left; the location of the protein of interest (expected size: 179 kDa) is indicated on the right. Rabbit IgG Purified Ms E
0.1 ml / €325.00
  OriGene Technologies, Inc.

RBBP2H1 / JARID1B antibody

RBBP2H1 / JARID1B Rabbit IgG Purified Hu
50 µg / €325.00
  OriGene Technologies, Inc.

RBBP2H1 / JARID1B antibody

RBBP2H1 / JARID1B Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

RBBP2H1 / JARID1B antibody

JARID1B monoclonal antibody (M02), clone 1G10. Western Blot analysis of JARID1B expression in NIH/3T3 ( Cat # L018V1 ). Mouse IgG2a 1G10 Ascites Hu E, WB
0.2 ml / €370.00
  Abnova Taiwan Corp.

RBBP2H1 / JARID1B antibody

RBBP2H1 / JARID1B Mouse IgG1 4F12 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

RBBP2H1 / JARID1B antibody

Western blot was performed on whole cell lysates from mouse fibroblasts ( Lane 1, NIH/3T3 ) and embryonic stem cells ( Lane 2, E14Tg2a ) with Jarid1b polyclonal antibody ( Cat # PAB14079 ), diluted 1 : 500 in BSA/PBS-Tween. Rabbit Ms E, WB
0.1 ml / €390.00
  Abnova Taiwan Corp.

RBBP2H1 / JARID1B antibody

Human Thymus; WB Suggested Anti-JMJD1B Antibody Titration: 2.5ug/ml. ELISA Titer: 1:12500. Positive Control: Human Thymus; JMJD1B antibody - C-terminal region (ARP39268_T100) in Human Thymus cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Can, Chk, Dros, Hu, Ms, Rt WB
0.1 mg / €310.00
  AVIVA Systems Biology

RBBP2H1 / JARID1B antibody

RBBP2H1 / JARID1B Rabbit Hu E, WB
50 µg / €440.00
  Novus Biologicals Inc.

RBBP2H1 / JARID1B antibody

Immunohistochemistry-Paraffin: JARID1B Antibody [NB100-97821] - FFPE section of human prostate carcinoma.  Affinity purified rabbit anti-Jarid1B used at a dilution of 1:500.  Detection: DAB staining using Immunohistochemistry Accessory Kit Rabbit IgG Aff - Purified Hu, Ms IP, P, WB
0.1 ml / €440.00
  Novus Biologicals Inc.

RBBP2H1 / JARID1B antibody

Immunohistochemistry-Paraffin: JARID1B Antibody [NBP1-84352] - Immunohistochemical staining of human prostate shows strong nuclear positivity in glandular cells. Rabbit IgG Aff - Purified Hu ICC/IF, P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

RBBP2H1 / JARID1B

RBBP2H1 / JARID1B Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

RBBP2H1 / JARID1B

RBBP2H1 / JARID1B Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

13 Item(s)

per page
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