RBBP2H1 / JARID1B antibody

Principal name

RBBP2H1 / JARID1B antibody

Alternative names for RBBP2H1 / JARID1B antibody

PLU-1, PLU1, Retinoblastoma-binding protein 2 homolog 1, CT31, Histone demethylase JARID1B, Jumonji/ARID domain-containing protein 1B

SwissProt ID

Q5F3R2 (Chick), Q80Y84 (Mouse), Q9UGL1 (Human)

Gene ID

10765 (KDM5B), 75605 (Kdm5b)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Dros (Drosophila), Ms (Mouse), Rt (Rat), African clawed frog

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of RBBP2H1 / JARID1B antibody

Jumonji AT-rich interactive domain 1B (JARID1B) also known as Jumonji/ARID domain-containing protein 1B, Lysine-specific demethylase 5B (KDM5B), Cancer/testis antigen 31 (CT31), Histone demethylase JARID1B, PLU-1, and Retinoblastoma-binding protein 2 homolog 1 (RBP2-H1), is a member of the JARID 1 family. The JARID 1 proteins (JARID1A, JARID1B, JARID1C and JARID1D) catalyze the demethylation of histones on lysine, and JARID1B specifically demethylates lysine 4 on Histone H3. JARID1B functions as a transcriptiol co-repressor for FOXG1B and PAX9. In addition, JARID1B may play a considerable role in cancer research as it assists in the propagation of breast cancer cells by repressing the tumor suppressor genes BRCA1 and HOXA5. Conversely, JARID1B acts as a direct suppressor of melanoma. As result, the JARID1B protein is up regulated in breast cancer and down regulated in melanoma and glioblastomas. In general, JARID1B expression is ubiquitous; with the highest expression seen in testis. JARID1B is subject to post translatiol phosphorylation and has two known isoforms; isoform 1: 175.6kDa and isoform 2: 179.4kDa.

General readings

Hu,Z., (2001) Oncogene 20 (47), 6946-6954

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

RBBP2H1 / JARID1B antibody

  Rabbit Polyclonal Lysine (K)-specific Demethylase 5B/KDM5B/JARID1B Antibody  
Immunohistochemistry: JARID1B Antibody [TA336866] - IHC analysis of JARID1B in human breast cancer xenograft using DAB with hematoxylin counterstain. Rabbit Purified Hu C, ICC/IF, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

RBBP2H1 / JARID1B antibody

  Rabbit Polyclonal Jarid1b Antibody  
WB was performed on whole cell lysates from mouse fibroblasts (NIH3T3) and embryonic stem cells (E14Tg2a) with the antibody against mouse Jarid1b, diluted 1:500 in BSA/PBS-Tween. The molecular weight marker (in kDa) is shown on the left; the location of the protein of interest (expected size: 179 kDa) is indicated on the right. Rabbit IgG Purified Ms E
0.1 ml / €325.00
  OriGene Technologies, Inc.

RBBP2H1 / JARID1B antibody

  Rabbit Polyclonal Anti-KDM5B Antibody  
Gel: 6%SDS-PAGE, Lysate: 40 ug, Lane 1-2: Hela cells, MCF7 cells, Primary antibody: (KDM5B Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 minutes Rabbit IgG Purified Hu, Ms E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

RBBP2H1 / JARID1B antibody

  Rabbit Polyclonal JARID1B Antibody  
RBBP2H1 / JARID1B Rabbit IgG Purified Hu
50 µg / €325.00
  OriGene Technologies, Inc.

RBBP2H1 / JARID1B antibody

RBBP2H1 / JARID1B Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

RBBP2H1 / JARID1B antibody

JARID1B monoclonal antibody (M02), clone 1G10. Western Blot analysis of JARID1B expression in NIH/3T3 ( Cat # L018V1 ). Mouse IgG2a 1G10 Ascites Hu E, WB
0.2 ml / €370.00
  Abnova Taiwan Corp.

RBBP2H1 / JARID1B antibody

RBBP2H1 / JARID1B Mouse IgG1 4F12 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

RBBP2H1 / JARID1B antibody

Western blot was performed on whole cell lysates from mouse fibroblasts ( Lane 1, NIH/3T3 ) and embryonic stem cells ( Lane 2, E14Tg2a ) with Jarid1b polyclonal antibody ( Cat # PAB14079 ), diluted 1 : 500 in BSA/PBS-Tween. Rabbit Ms E, WB
0.1 ml / €390.00
  Abnova Taiwan Corp.

RBBP2H1 / JARID1B antibody

Human Thymus; WB Suggested Anti-JMJD1B Antibody Titration: 2.5ug/ml. ELISA Titer: 1:12500. Positive Control: Human Thymus; JMJD1B antibody - C-terminal region (ARP39268_T100) in Human Thymus cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Can, Chk, Dros, Hu, Ms, Rt WB
0.1 mg / €310.00
  AVIVA Systems Biology

CRISPR

Catalog No. Species Donor Vector  

KDM5B - human gene knockout kit via CRISPR

KDM5B - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

KDM5B - human gene knockout kit via CRISPR

KDM5B - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

KDM5B - human gene knockout kit via CRISPR

KDM5B - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

KDM5B - human gene knockout kit via CRISPR

KDM5B - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Kdm5b - mouse gene knockout kit via CRISPR

Kdm5b - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Kdm5b - mouse gene knockout kit via CRISPR

Kdm5b - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Kdm5b - mouse gene knockout kit via CRISPR

Kdm5b - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Kdm5b - mouse gene knockout kit via CRISPR

Kdm5b - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

RBBP2H1 / JARID1B

RBBP2H1 / JARID1B Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

RBBP2H1 / JARID1B

RBBP2H1 / JARID1B Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, KDM5B (mGFP-tagged) - Human lysine (K)-specific demethylase 5B (KDM5B), 200 uL, >10^7 TU/mL

Lenti ORF particles, KDM5B (mGFP-tagged) - Human lysine (K)-specific demethylase 5B (KDM5B), 200 uL, >10^7 TU/mL  
200 µl / €2,530.00
  OriGene Technologies, Inc.

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