RBBP7 / RBAP46 antibody

Principal name

RBBP7 / RBAP46 antibody

Alternative names for RBBP7 / RBAP46 antibody

RBBP-7, Histone-binding protein RBBP7, Retinoblastoma-binding protein 7, Nucleosome-remodeling factor subunit RBAP46, Retinoblastoma-binding protein p46

SwissProt ID

Q16576 (Human), Q3SWX8 (Bovin), Q60973 (Mouse), Q71UF4 (Rat), Q7ZTY4 (Danre), Q8AVH1 (Xenla), Q9I8G9 (Chick)

Gene ID

5931 (RBBP7)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), Rb (Rabbit), Ze (Zebrafish)

Available hosts

Rabbit, Mouse

Available applications

Frozen Sections (C), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Enzyme Immunoassay (E), Immunoprecipitation (IP), Flow Cytometry (F), Luminex (LMNX)

Background of RBBP7 / RBAP46 antibody

Retinoblastoma protein (Rb) associated protein 46 (RbAp 46) is a nuclear protein that has been shown to interact directly with retinoblastoma protein and is a component of the mSin3 corepressor complex as are the histone deacetylase proteins (HDACs). RbAp 46 shares about 75% sequence identity with the closely related RbAp 48, and appears to be functionally related to the yeast MSI 1 protein in that overexpression of RbAp 46 suppresses heat shock sensitivity in a RAS pathway dependent manner. RbAp 46 has also been demonstrated to be up-regulated by the Wilms? tumor suppressor gene product, WT1. Additionally, cells transfected with RbAp46 have shown strong inhibition of growth.

General readings

General / background references:Guan LS et al. Induction of Rb-associated protein (RbAp46) by Wilms' tumor suppressor WT1 mediates growth inhibition. J Biol Chem 273:27047-50 (1998). PubMed PMID: 9765217
Brehm A et al. Retinoblastoma protein recruits histone deacetylase to repress transcription. Nature 391:597-601 (1998). PubMed PMID: 9468139
Qian YW & Lee EY Dual retinoblastoma-binding proteins with properties related to a negative regulator of ras in yeast. J Biol Chem 270:25507-13 (1995). PubMed PMID: 7503932

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

RBBP7 / RBAP46 antibody

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-RBBP7 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503667) Mouse IgG1 OTI5A4 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

RBBP7 / RBAP46 antibody

Immunohistochemical staining of paraffin-embedded Human endometrium tissue within the normal limits using anti-RBBP7 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503749) Mouse IgG2b OTI4C9 Purified Hu F, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

RBBP7 / RBAP46 antibody

Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-RBBP7 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504004) Mouse IgG1 OTI2D8 Purified Hu ICC/IF, P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

RBBP7 / RBAP46 antibody

WB Suggested Anti-RBBP7 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: Human Thymus Rabbit IgG Purified Bov, Can, Eq, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

RBBP7 / RBAP46 antibody

WB Suggested Anti-RBBP7 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: HepG2 cell lysate Rabbit IgG Purified Bov, Can, Eq, Hu, Ms, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

RBBP7 / RBAP46 antibody

Anti-RBBP7 mouse monoclonal antibody (TA503809) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY RBBP7(RC217969). Mouse IgG1 OTI3A12 Purified Hu ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

RBBP7 / RBAP46 antibody

RBBP7 ELISA with 2D8 Capture (TA600416) and Anti-Tag 1B12 Detection (TA700050) Antibodies. Substrate used: Recombinant Human RBBP7 (TP317969) Mouse IgG1 OTI2D8 Purified Hu E, LMNX
0.1 mg / €325.00
  OriGene Technologies, Inc.

RBBP7 / RBAP46 antibody

RBBP7 ELISA with 4C9 Capture (TA600417) and Anti-Tag 1B12 Detection (TA700050) Antibodies. Substrate used: Recombinant Human RBBP7 (TP317969) Mouse IgG1 OTI4C9 Purified Hu E, LMNX
0.1 mg / €325.00
  OriGene Technologies, Inc.

RBBP7 / RBAP46 antibody

RBBP7 Luminex ELISA with Anti-Tag 1B12 Capture (TA600050) and 4C9 Detection (TA700416) Antibodies. Substrate used: Recombinant Human RBBP7 (TP317969) Mouse IgG1 OTI4C9 Purified Hu LMNX
50 µg / €345.00
  OriGene Technologies, Inc.

RBBP7 / RBAP46 (N-term) antibody

Western blot analysis of RBBP7 Antibody (N-term) (AP18177PU-N) in 293 cell line lysates (35ug/lane). RBBP7 (arrow) was detected using the purified Pab. Rabbit Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

RBBP7 / RBAP46 (Center) antibody

Western blot analysis of RBBP7 (arrow) using RBBP7 / RBAP46 Antibody Cat.-No AP53600PU-N. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the RBBP7 gene. Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

RBBP7 / RBAP46 antibody

Human Thymus; WB Suggested Anti-RBBP7 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: Human Thymus; RBBP7 antibody - N-terminal region (ARP56517_P050) in Human Thymus cells using Western Blot Rabbit Aff - Purified Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

RBBP7 / RBAP46 antibody

Human HepG2; WB Suggested Anti-RBBP7 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: HepG2 cell lysate; RBBP7 antibody - middle region (ARP56518_P050) in Human HepG2 cells using Western Blot Rabbit Aff - Purified Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

RBBP7 / RBAP46 antibody

RBBP7 / RBAP46 Rabbit Biotin Hu WB
0.1 mg / €360.00
  Novus Biologicals Inc.

RBBP7 / RBAP46 antibody

Figure 1 shows immunolocalization of RbAp46 in HeLa cells using NB120-3535. Figure 2 shows a Western blot of RbAp46 on 1) Du-145 2) LNCaP and 3) Hep-G2 cell extracts using NB120-3535. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

RBBP7 / RBAP46

RBBP7 / RBAP46 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

RBBP7 / RBAP46

RBBP7 / RBAP46 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

RBBP7 / RBAP46

RBBP7 / RBAP46 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

RBBP7 overexpression lysate

RBBP7 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

19 Item(s)

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