RBL1 antibody

Principal name

RBL1 antibody

Alternative names for RBL1 antibody

Retinoblastoma-like protein 1, 107 kDa retinoblastoma-associated protein, p107, pRb1

SwissProt ID

P28749 (Human), P28749-2, Q64701 (Mouse)

Gene ID

5933 (RBL1), 19650 (Rbl1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Chk (Chicken), Eq (Equine), Por (Porcine), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of RBL1 antibody

RBL1 is similar in sequence and possibly function to the product of the retinoblastoma 1 (RB1) gene. The RB1 gene product is a tumor suppressor protein that appears to be involved in cell cycle regulation, as it is phosphorylated in the S to M phase transition and is dephosphorylated in the G1 phase of the cell cycle. Both the RB1 protein and the product of this gene can form a complex with adenovirus E1A protein and SV40 large T-antigen, with the SV40 large T-antigen binding only to the unphosphorylated form of each protein. In addition, both proteins can inhibit the transcription of cell cycle genes containing E2F binding sites in their promoters. Due to the sequence and biochemical similarities with the RB1 protein, it is thought that the protein encoded by this gene may also be a tumor suppressor. The protein encoded by this gene is similar in sequence and possibly function to the product of the retinoblastoma 1 (RB1) gene. The RB1 gene product is a tumor suppressor protein that appears to be involved in cell cycle regulation, as it is phosphorylated in the S to M phase transition and is dephosphorylated in the G1 phase of the cell cycle. Both the RB1 protein and the product of this gene can form a complex with adenovirus E1A protein and SV40 large T-antigen, with the SV40 large T-antigen binding only to the unphosphorylated form of each protein. In addition, both proteins can inhibit the transcription of cell cycle genes containing E2F binding sites in their promoters. Due to the sequence and biochemical similarities with the RB1 protein, it is thought that the protein encoded by this gene may also be a tumor suppressor. Two transcript variants encoding different isoforms have been found for this gene.

18 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

RBL1 antibody

  Rabbit Polyclonal Anti-RBL1 Antibody  
WB Suggested Anti-RBL1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: COLO205 cell lysate Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

RBL1 antibody

  Rabbit Polyclonal Anti-RBL1 Antibody  
WB Suggested Anti-RBL1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: Human Muscle Rabbit IgG Purified Bov, Can, Eq, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

RBL1 antibody

Figure 1. Western Blot analysis of AM05250PU-N antibody. Mouse IgG1 KAB6 Purified Hu, Ms, Rt WB
0.1 mg / €370.00
  Acris Antibodies GmbH

RBL1 pSer975 antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

RBL1 pThr369 antibody

Immunohistochemistry analysis of paraffin-embedded human lymph node, using RBL1 (Phospho-Thr369) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, P
50 µg / €230.00
  Assay Biotech

RBL1 pThr369 antibody

Immunohistochemistry analysis of paraffin-embedded human lymph node, using RBL1 (Phospho-Thr369) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, P
0.1 mg / €330.00
  Assay Biotech

RBL1 antibody

Immunofluorescence analysis of NIH-3T3 cells, using RBL1 (Ab-369) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, ICC/IF
50 µg / €230.00
  Assay Biotech

RBL1 antibody

Immunofluorescence analysis of NIH-3T3 cells, using RBL1 (Ab-369) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, ICC/IF
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

Rbl1 - mouse gene knockout kit via CRISPR

Rbl1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Rbl1 - mouse gene knockout kit via CRISPR

Rbl1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Rbl1 - mouse gene knockout kit via CRISPR

Rbl1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Rbl1 - mouse gene knockout kit via CRISPR

Rbl1 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

RBL1 overexpression lysate

RBL1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, RBL1 (mGFP-tagged)-Human retinoblastoma-like 1 (p107) (RBL1), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, RBL1 (mGFP-tagged)-Human retinoblastoma-like 1 (p107) (RBL1), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €2,150.00
  OriGene Technologies, Inc.

Lenti ORF particles, RBL1 (mGFP-tagged) - Human retinoblastoma-like 1 (p107) (RBL1), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, RBL1 (mGFP-tagged) - Human retinoblastoma-like 1 (p107) (RBL1), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,320.00
  OriGene Technologies, Inc.

Lenti ORF particles, RBL1 (Myc-DDK-tagged)-Human retinoblastoma-like 1 (p107) (RBL1), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, RBL1 (Myc-DDK-tagged)-Human retinoblastoma-like 1 (p107) (RBL1), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,940.00
  OriGene Technologies, Inc.

Lenti ORF particles, RBL1 (Myc-DDK tagged) - Human retinoblastoma-like 1 (p107) (RBL1), transcript variant 2 , 200 uL, >10^7 TU/mL

Lenti ORF particles, RBL1 (Myc-DDK tagged) - Human retinoblastoma-like 1 (p107) (RBL1), transcript variant 2 , 200 uL, >10^7 TU/mL  
200 µl / €1,180.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Rbl1 (GFP-tagged) - Mouse retinoblastoma-like 1 (p107) (Rbl1), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, Rbl1 (GFP-tagged) - Mouse retinoblastoma-like 1 (p107) (Rbl1), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,240.00
  OriGene Technologies, Inc.

18 Item(s)

per page
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