RCC1 / CHC1 antibody

Principal name

RCC1 / CHC1 antibody

Alternative names for RCC1 / CHC1 antibody

RCC1-I, Regulator of chromosome condensation, Chromosome condensation protein 1, Cell cycle regulatory protein

SwissProt ID

P18754 (Human), P21827 (Yeast), P25183 (Xenla), Q8VE37 (Mouse)

Gene ID

1104 (RCC1), 100088 (Rcc1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), EPair for Elisa (EPair), Immunoprecipitation (IP)

Background of RCC1 / CHC1 antibody

RCC1 (regulator of chromosome condensation) is a 45 kD nuclear protein containing RCC1 repeats.This widely expressed protein associates with chromosomes and acts as a guanine nucleotide exchange factor (GEF) protein for Ras-related GTPase Ran. RCC1 is thought to maintain the Ran GTP gradient required for nucleocytoplasmic transport and spindle assembly across the interphase nuclear envelope and on condensed mitotic chromosomes. RCC1 regulates cell cycle and also plays a role in nuclear pore transport. Defects in RCC1 results in abnormal chromosome segregation and genomic instability. RCC1 is transcriptionally activated by Myc through E-box elements. RCC1 binds to chromatin in a binary complex with Ran. The Poly6164 antibody recognizes the N-terminal region of the human and mouse RCC1 protein and has been shown to be useful for Western blotting.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

RCC1 / CHC1 antibody

Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE) Mouse IgG1 2F1 Purified Hu E, ICC/IF, P, WB
50 µg / €530.00
  Acris Antibodies GmbH

RCC1 / CHC1 antibody

  Rabbit polyclonal anti-RCC1 antibody  
Western blot analysis of extracts from LOVO cells, using RCC1 antibody (#TA313618).The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

RCC1 / CHC1 antibody

  Rabbit Polyclonal anti-RCC1 Antibody  
Hela cell nuclear extract was resolved by electrophoresis, transferred to nitrocellulose, and probed with rabbit anti-RCC1 antibody. Proteins were visualized using a donkey anti-rabbit secondary conjugated to HRP and a chemiluminescence detection system. Rabbit IgG Poly6164 Purified Hu, Ms WB
0.2 ml / €325.00
  OriGene Technologies, Inc.

RCC1 / CHC1 antibody

  Rabbit Polyclonal anti-RCC1 Antibody  
Hela cell nuclear extract was resolved by electrophoresis, transferred to nitrocellulose, and probed with rabbit anti-RCC1 antibody. Proteins were visualized using a donkey anti-rabbit secondary conjugated to HRP and a chemiluminescence detection system. Rabbit Poly6164 Purified Hu, Ms WB
50 µl / €248.00
  OriGene Technologies, Inc.

RCC1 / CHC1 antibody

  Rabbit Polyclonal anti-RCC1 Antibody  
Human Colon Carcinoma stained with anti-RCC1 antibody. Rabbit Purified Hu P
0.1 ml / €325.00
  OriGene Technologies, Inc.

RCC1 / CHC1 (13-21) antibody

Immunocytochemical detection of RCC1 on 4% paraformaldehyde fixed HepG2 cells (left) and HeLa cells (right) with AM26601AF-N. Mouse IgG1 3D11 Azide Free Hu, Ms, Rt
0.1 mg / €390.00
  Acris Antibodies GmbH

RCC1 / CHC1 antibody

Human Skin (formalin-fixed, paraffin-embedded) stained with RCC1 antibody AP22629SU-N at 1/100 followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Rabbit Serum Hu ICC/IF, IP, P, WB
50 µl / €470.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

RCC1 - human gene knockout kit via CRISPR

RCC1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

RCC1 - human gene knockout kit via CRISPR

RCC1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Rcc1 - mouse gene knockout kit via CRISPR

Rcc1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Rcc1 - mouse gene knockout kit via CRISPR

Rcc1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Rcc1 - mouse gene knockout kit via CRISPR

Rcc1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Rcc1 - mouse gene knockout kit via CRISPR

Rcc1 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

RCC1 / CHC1 (transcript variant 3)

  Recombinant protein of human SNHG3-RCC1 readthrough transcript (SNHG3-RCC1), transcript variant 3  
RCC1 / CHC1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

RCC1 / CHC1 (transcript variant 3)

  Recombinant protein of human regulator of chromosome condensation 1 (RCC1), transcript variant 3  
RCC1 / CHC1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, RCC1 (mGFP-tagged) - Human regulator of chromosome condensation 1 (RCC1), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, RCC1 (mGFP-tagged) - Human regulator of chromosome condensation 1 (RCC1), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Rcc1 (GFP-tagged) - Mouse regulator of chromosome condensation 1 (Rcc1), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, Rcc1 (GFP-tagged) - Mouse regulator of chromosome condensation 1 (Rcc1), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Rcc1 (Myc-DDK-tagged) - Mouse regulator of chromosome condensation 1 (Rcc1), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, Rcc1 (Myc-DDK-tagged) - Mouse regulator of chromosome condensation 1 (Rcc1), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

18 Item(s)

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