Reelin antibody

Principal name

Reelin antibody

Alternative names for Reelin antibody

RELN

SwissProt ID

O93574, P58751, P78509, Q60841, Q9N117

Gene ID

5649 (RELN)

Available reactivities

All Species, Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Immunoprecipitation (IP), Western blot / Immunoblot (WB), Enzyme Immunoassay (E)

Background of Reelin antibody

Reelin (or Reln) is a large glycoprotein that is secreted by Cajal-Retzius cells in the forebrain and by granule neurons in the cerebellum. Reelin was shown to be mutated in “reeler” mice, a mutation that is associated with widespread disruption of laminated regions of the brain, leading to impaired motor coordination, tremors and ataxia. Reelin protein expression is complex and changes throughout development. Reelin appears to function upstream of Dab1 in a signaling pathway that controls cell positioning in the developing brain and is also thought to be a direct effector of the neurotrophin BDNF.

General readings

This product has been used in:Tissir F & Goffinet AM Reelin and brain development. Nat Rev Neurosci 4:496-505 (2003). PubMed PMID: 12778121
de Bergeyck V et al. A panel of monoclonal antibodies against reelin, the extracellular matrix protein defective in reeler mutant mice. J Neurosci Methods 82:17-24 (1998). PubMed PMID: 10223511
de Bergeyck V et al. A truncated Reelin protein is produced but not secreted in the 'Orleans' reeler mutation (Reln[rl-Orl]). Brain Res Mol Brain Res 50:85-90 (1997). PubMed PMID: 9406921

3 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Reelin antibody

ELISA: Reelin Antibody Rabbit IgG Purified Hu E
0.1 mg / €325.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

RELN overexpression lysate

RELN overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, RELN (Myc-DDK tagged) - Human reelin (RELN), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, RELN (Myc-DDK tagged) - Human reelin (RELN), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €2,280.00
  OriGene Technologies, Inc.

3 Item(s)

per page
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