Reelin antibody

Principal name

Reelin antibody

Alternative names for Reelin antibody

RELN

SwissProt ID

O93574, P58751, P78509, Q60841, Q9N117

Gene ID

5649 (RELN)

Available reactivities

All Species, Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Immunoprecipitation (IP), Western blot / Immunoblot (WB), Enzyme Immunoassay (E)

Background of Reelin antibody

Reelin (or Reln) is a large glycoprotein that is secreted by Cajal-Retzius cells in the forebrain and by granule neurons in the cerebellum. Reelin was shown to be mutated in “reeler” mice, a mutation that is associated with widespread disruption of laminated regions of the brain, leading to impaired motor coordination, tremors and ataxia. Reelin protein expression is complex and changes throughout development. Reelin appears to function upstream of Dab1 in a signaling pathway that controls cell positioning in the developing brain and is also thought to be a direct effector of the neurotrophin BDNF.

General readings

This product has been used in:Tissir F & Goffinet AM Reelin and brain development. Nat Rev Neurosci 4:496-505 (2003). PubMed PMID: 12778121
de Bergeyck V et al. A panel of monoclonal antibodies against reelin, the extracellular matrix protein defective in reeler mutant mice. J Neurosci Methods 82:17-24 (1998). PubMed PMID: 10223511
de Bergeyck V et al. A truncated Reelin protein is produced but not secreted in the 'Orleans' reeler mutation (Reln[rl-Orl]). Brain Res Mol Brain Res 50:85-90 (1997). PubMed PMID: 9406921

5 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Reelin antibody

ELISA: Reelin Antibody Rabbit IgG Purified Hu E
0.1 mg / €325.00
  OriGene Technologies, Inc.

Reelin antibody

ELISA: Reelin Antibody [32540002] Rabbit Hu E
50 µg / €520.00
  Novus Biologicals Inc.

Reelin antibody

Immunocytochemistry: Reelin Antibody (142) [NB600-1080] - Mouse anti-Reelin staining of Reelin-positive Cajal-Retzius neurons in a human fetal cerebral cortex at 21 weeks of gestation, using anti-Reelin MAB5366 (dilution 1:500). Photo courtesy of Dr. G. Meyer. Mouse IgG1 142 Purified All Species ICC/IF, IP, P, WB
50 µg / €390.00
  Novus Biologicals Inc.

Reelin antibody

Immunohistochemistry: Reelin Antibody (G10) [NB600-1081] - Mouse anti-Reelin staining of embryonic cerebral cortex at 15 days in utero, with the pial surface above and the ventricle below. The positive zone is the Cajal-Retzius cell layer in the marginal zone, positive for reelin using NB600-1081. Mouse IgG1 G10 Purified Hu, Ms, Rt P, WB
50 µg / €380.00
  Novus Biologicals Inc.

Lysates

Catalog No.    

RELN overexpression lysate

RELN overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

5 Item(s)

per page
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