Relaxin receptor 2 / RXFP2 antibody

Principal name

Relaxin receptor 2 / RXFP2 antibody

Alternative names for Relaxin receptor 2 / RXFP2 antibody

G-protein coupled receptor 106, GPR106, GREAT, LGR8, Relaxin family peptide receptor 2, Leucine-rich repeat-containing G-protein coupled receptor 8, G-protein coupled receptor affecting testicular descent

SwissProt ID

Q5XM32 (Canfa), Q8WXD0 (Human), Q91ZZ5 (Mouse)

Gene ID

122042 (RXFP2), 450220

Available reactivities

Hu (Human), Ms (Mouse), Bt (Bat), Eq (Equine), Mky (Monkey)

Available hosts

Rabbit

Available applications

Paraffin Sections (P), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Enzyme Immunoassay (E), Frozen Sections (C)

Background of Relaxin receptor 2 / RXFP2 antibody

Relaxins are endocrine and autocrine/paracrine hormones belonging to the insulin gene superfamily. In several mammalian species, relaxin is best known for its role during pregnancy and parturition, when it is produced by the corpora lutea of ovaries and other reproductive tissues. The secretion of relaxin into the blood stream just before parturition results in a marked softening and lengthening of the pubic symphysis and a softening of the cervix, which facilitates the birth process. Also, by inhibiting uterine contractions, relaxin may influence the timing of parturition. Two previously characterized orphan receptors designated relaxin receptor 1 (LGR7) and 2 (LGR8) bind relaxin in several tissues, including reproductive tissues, brain, and heart. Upon ligand binding, the relaxin receptors activate adenylate cyclases through Gs proteins. Expression of the relaxin receptors in tissues other than reproductive ones suggests that they have additional physiological functions, such as regulating blood pressure and controlling vascular volume in the heart.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Relaxin receptor 2 / RXFP2 (Extracell. Dom.) antibody

Anti-RXFP2 / LGR8 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Hu P
50 µg / €379.00
  OriGene Technologies, Inc.

Relaxin receptor 2 / RXFP2 (Cytopl. Dom.) antibody

Anti-RXFP2 antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Hu P, WB
50 µg / €379.00
  OriGene Technologies, Inc.

Relaxin receptor 2 / RXFP2 antibody

Western blot analysis of Relaxin Receptor 2 Antibody (Cat.-No AP01337PU-N) at 1/ 500 dilution: Lane 1: HEK293T whole cell lysate.Lane 2: RAW264.7 whole cell lysate.Lane 3: H9C2 whole cell lysate. Rabbit Aff - Purified Hu, Ms ICC/IF, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Relaxin receptor 2 / RXFP2 antibody

Anti-RXFP2 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Purified Hu
50 µg / €379.00
  OriGene Technologies, Inc.

Relaxin receptor 2 / RXFP2 antibody

Anti-RXFP2 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Purified Hu, Mky
50 µg / €379.00
  OriGene Technologies, Inc.

Relaxin receptor 2 / RXFP2 (144-158) antibody

Immunohistochemistry of RXFP2 staining in Paraffin Section of Human testis. The section was incubated with AP23449SU (1/4000) overnight and detected using ABC stainig Kit. DAB was used as the chromogen. The section was counter-stained with haemalaun. 
A: AP23449SU recognizes interstitial Leydig cells and germ cells (arrow heads). 
B: Preimmune serum at the same dilution. 
Scale bar = 50 µm 
Anand-Ivell R et al. (2006) Biol Reprod 74:945-953. Rabbit Serum Hu ICC/IF, P
0.1 ml / €540.00
  Acris Antibodies GmbH

Relaxin receptor 2 / RXFP2 (144-158) antibody

Immunohistochemistry of RXFP2 staining in Paraffin Section of Human testis. The section was incubated with AP23449SU (1/4000) overnight and detected using ABC stainig Kit. DAB was used as the chromogen. The section was counter-stained with haemalaun. 
A: AP23449SU recognizes interstitial Leydig cells and germ cells (arrow heads). 
B: Preimmune serum at the same dilution. 
Scale bar = 50 µm 
Anand-Ivell R et al. (2006) Biol Reprod 74:945-953. Rabbit Serum Hu ICC/IF, P
20 µl / €190.00
  Acris Antibodies GmbH

Relaxin receptor 2 / RXFP2 antibody

Relaxin receptor 2 / RXFP2 Rabbit Serum Hu C, E, WB
0.2 ml / €400.00
  Acris Antibodies GmbH

Relaxin receptor 2 / RXFP2 antibody

Western blot analysis of extracts from Jurkat cells, using RXFP2 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, WB
50 µg / €205.00
  Assay Biotech

Relaxin receptor 2 / RXFP2 antibody

Western blot analysis of extracts from Jurkat cells, using RXFP2 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, WB
0.1 mg / €310.00
  Assay Biotech

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Relaxin receptor 2 / RXFP2

Relaxin receptor 2 / RXFP2 Human
10 µg / €540.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

RXFP2 overexpression lysate

RXFP2 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

12 Item(s)

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