REM1 antibody

Principal name

REM1 antibody

Alternative names for REM1 antibody

GES, REM, GTP-binding protein REM 1, GTPase-regulating endothelial cell sprouting, Rad and Gem-like GTP-binding protein 1

SwissProt ID

O14332 (Schpo), O35929 (Mouse), O75628 (Human)

Gene ID

28954 (REM1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit), Sh (Sheep)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunoprecipitation (IP), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of REM1 antibody

REM (Rad and Gem related GTP binding protein) is a member of the Rad/Gem/Kir subfamily of Ras-like GTPases and shares with other members of this subfamily some unusual structural features. Among these are nonconservative amino acid substitutions within guanine nucleotide binding and hydrolysis domains, unique effector domains, extended N- and C-termini, and a conserved C-terminal sequence thought to mediate membrane association but lacking a classical isoprenylation motif. REM, with a predicted molecular weight of 32.9 kDa, is most highly expressed in cardiac muscle and is expressed at more moderate levels in lung, kidney and skeletal muscle. REM is phosphorylated in vivo and has been shown to interact with several 14-3-3 isoforms. It has been reported that the GTP-bound form of a related Ras-like GTPase, GEM/kir, inhibits high-voltage activated Ca2+ channel activities by interacting directly with the ? subunit. The reduced channel activities are the result of a decreased a-subunit expression at the plasma membrane. This inhibition of L-type Ca2+ channels prevents Ca2+-triggered exocytosis in hormone-secreting cells. There are data that suggest that REM similarly regulates Ca2+ channel expression.

General readings

General / background references:Pan JY et al. Ges, A human GTPase of the Rad/Gem/Kir family, promotes endothelial cell sprouting and cytoskeleton reorganization. J Cell Biol 149:1107-16 (2000). PubMed PMID: 10831614
Finlin BS & Andres DA Phosphorylation-dependent association of the Ras-related GTP-binding protein Rem with 14-3-3 proteins. Arch Biochem Biophys 368:401-12 (1999). PubMed PMID: 10441394
Finlin BS & Andres DA Rem is a new member of the Rad- and Gem/Kir Ras-related GTP-binding protein family repressed by lipopolysaccharide stimulation. J Biol Chem 272:21982-8 (1997). PubMed PMID: 9268335

18 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

REM1 antibody

WB Suggested Anti-REM1 Antibody Titration: 0.2-1 ug/ml; Positive Control: Hela cell lysate Rabbit IgG Purified Can, Eq, GP, Ms, Por, Rb, Sh WB
50 µg / €325.00
  OriGene Technologies, Inc.

REM1 antibody

Immunohistochemistry (IHC) analyzes of Rad GTPase antibody (Cat.-No.: AP01407PU-N) in paraffin-embedded human heart tissue Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

REM1 antibody

REM1 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

REM1 antibody

Immunofluorescence of purified MaxPab antibody to REM1 on HeLa cell. [antibody concentration 10 ug/ml] Mouse Serum Hu E(detection), ICC/IF, WB
50 µl / €370.00
  Abnova Taiwan Corp.

REM1 antibody

Immunofluorescence of purified MaxPab antibody to REM1 on HeLa cell. [antibody concentration 10 ug/ml] Mouse Purified Hu E(detection), ICC/IF, WB
50 µg / €370.00
  Abnova Taiwan Corp.

REM1 antibody

REM1 Mouse IgG2a 3A9 Purified Hu E
0.1 mg / €370.00
  Abnova Taiwan Corp.

REM1 antibody

Human HeLa; WB Suggested Anti-REM1 Antibody Titration: 0.2-1 ug/ml. Positive Control: Hela cell lysate; REM1 antibody - N-terminal region (ARP54963_P050) in Human HeLa cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

REM1 antibody

REM1 Mouse IgG1 24E4 Purified Hu, Ms IP, WB
50 µg / €380.00
  Novus Biologicals Inc.

REM1 antibody

Immunohistochemistry: Rad GTPase Antibody [NBP1-00998] - Immunohistochemistry (IHC) analyzes of Rad GTPase (L80) antibody in paraffin-embedded human heart tissue. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €420.00
  Novus Biologicals Inc.

REM1 antibody

Western Blot: REM1 Antibody [NBP1-55506] - This Anti-REM1 antibody was used in Western Blot of Hela       tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu WB
50 µg / €440.00
  Novus Biologicals Inc.

REM1 antibody

Western Blot: REM1 Antibody (EP4482) [NBP1-95186] (A) C2C12 and (B) SW1353 cell lysates using anti-REM. Rabbit EP4482 Purified Hu, Ms, Rt WB
0.1 ml / €420.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

REM1

REM1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

REM1

REM1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

REM1

REM1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

REM1

REM1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

REM1

REM1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

REM1 293T Cell Transient Overexpression Lysate(Denatured)

REM1 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

REM1 overexpression lysate

REM1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

18 Item(s)

per page
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