Renin antibody

Principal name

Renin antibody

Alternative names for Renin antibody

REN, Angiotensinogenase, angiotensin-forming enzyme, HNFJ2

SwissProt ID

P00797 (Human), P08424 (Rat), P52115 (Sheep), Q6DYE7 (Canfa)

Gene ID

5972 (REN), 24715 (Ren)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Can (Canine), Prim (Primate), Por (Porcine), Bov (Bovine), Eq (Equine), GP (Guinea Pig), Rb (Rabbit), Sh (Sheep)

Available hosts

Mouse, Sheep, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Functional assay (FN)

Background of Renin antibody

Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Mutations in this gene have been shown to cause familial hyperproreninemia.Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined. Mutations in this gene have been shown to cause familial hyperproreninemia.

General readings

Gribouval O., et al. (2005) Nat. Genet. 37:964-968Zivna M., et al. (2009) Am. J. Hum. Genet. 85:204-213

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Renin antibody

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-REN mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA807365) Mouse IgG1 OTI2F10 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Renin antibody

Renin antibody [N2C2], Internal detects REN protein by Western blot analysis. A. 30 ug K562 whole cell lysate/extract. 10 % SDS-PAGE. Renin antibody [N2C2], Internal (TA308950) dilution: 1:1000 Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Renin antibody

Western blot analysis of extracts from Jurkat cells, using REN antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Renin antibody

Western blot analysis of extracts of various cell lines, using REN antibody. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Renin antibody

WB Suggested Anti-REN Antibody Titration: 2.5 ug/ml; Positive Control: HepG2 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt, Sh WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Renin antibody

Immunohistochemical staining of paraffin-embedded Human colon tissue within the normal limits using anti-REN mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA807103)(1:150) Mouse IgG2a OTI1D3 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Renin antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY REN (RC208382, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-REN.(1:500) Mouse IgG1 OTI4A3 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Renin antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY REN (RC208382, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-REN. Mouse IgG1 OTI2B9 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Renin antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY REN (RC208382, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-REN.(1:2000) Mouse IgG2b OTI2A2 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Renin antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY REN (RC208382, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-REN.(1:500) Mouse IgG1 OTI3E4 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Renin antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY REN (RC208382, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-REN.(1:2000) Mouse IgG1 OTI1A10 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Renin antibody

Renin Sheep Purified Ms, Rt E, P, WB
1 mg / €620.00
  Acris Antibodies GmbH

Renin (full length) antibody

Kidney: Formalin-Fixed Paraffin-Embedded (FFPE) Sheep Purified Hu E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

Renin antibody

Figure 1. Western blot analysis of REN in HepG2 Cell Lysate using REN antibody at 2.5 ?g/ml (12% gel). Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 mg / €410.00
  Acris Antibodies GmbH

Renin antibody

REN monoclonal antibody (M01), clone 2H2 Western Blot analysis of REN expression in K-562 ( Cat # L009V1 ). Mouse IgG1 2H2 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Renin antibody

Renin Mouse IgG1 3B5 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Renin antibody

Renin Mouse IgG1 244/1 RH12 Hu E
1 mg / €1,340.00
  Abnova Taiwan Corp.

Renin antibody

Renin Mouse IgG1 244/OE6 Hu E
1 mg / €1,340.00
  Abnova Taiwan Corp.

Renin antibody

Renin Mouse IgG1 257/A5 GC10 AH4 Hu E
1 mg / €1,340.00
  Abnova Taiwan Corp.

Renin antibody

Renin Mouse IgG1 243/3 JG4 Hu E
1 mg / €1,340.00
  Abnova Taiwan Corp.

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