RET antibody

Principal name

RET antibody

Alternative names for RET antibody

C-ret, CDHF12, Proto-oncogene tyrosine-protein kinase receptor ret, Cadherin family member 12

SwissProt ID

P07949 (Human), P35546 (Mouse)

Gene ID

5979 (RET), 19713 (Ret)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Rb (Rabbit), Mky (Monkey)

Available hosts

Mouse, Goat, Rabbit, Chicken, Rat

Available applications

Paraffin Sections (P), Frozen Sections (C), Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Flow Cytometry (F), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of RET antibody

Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. Phosphorylates PTK2/FAK1. Regulates both cell death/survival balance and positional information. Required for the molecular mechanisms orchestration during intestine organogenesis; involved in the development of enteric nervous system and renal organogenesis during embryonic life, and promotes the formation of Peyer's patch-like structures, a major component of the gut-associated lymphoid tissue. Modulates cell adhesion via its cleavage by caspase in sympathetic neurons and mediates cell migration in an integrin (e.g. ITGB1 and ITGB3)-dependent manner. Involved in the development of the neural crest. Active in the absence of ligand, triggering apoptosis through a mechanism that requires receptor intracellular caspase cleavage. Acts as a dependence receptor; in the presence of the ligand GDNF in somatotrophs (within pituitary), promotes survival and down regulates growth hormone (GH) production, but triggers apoptosis in absence of GDNF. Regulates nociceptor survival and size. Triggers the differentiation of rapidly adapting (RA) mechanoreceptors. Mediator of several diseases such as neuroendocrine cancers; these diseases are characterized by aberrant integrins-regulated cell migration.

General readings

Suggested References:
1. Nosrat CA, et al. Brain Res. 115: 410-422 (1997).
2. Williams GH, et al. Journal of Pathology. 180: 138-141 (1996).
3. Nakamura T, et al. Journal of Pathology. 172:255-260 (1994).

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

RET (N-term) antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

RET antibody

Proximity Ligation Analysis (PLA) of protein-protein interactions between RET and MAPK1 HeLa cells were stained with anti-RET rabbit purified polyclonal 1:1200 and anti-MAPK1 mouse monoclonal antibody 1:50. Signals were detected by Duolink® 30 Detection Kit 613(red), and nuclei were counterstained with DAPI (blue). Each red dot represents the detection of protein-protein interaction complex. Rabbit Purified Hu, Ms E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

RET antibody

RET monoclonal antibody (M07), clone 1C6. Western Blot analysis of RET expression in NIH/3T3(Cat # L018V1 ). Mouse IgG2a 1C6 Purified Hu E
0.1 mg / €370.00
  Abnova Taiwan Corp.

RET antibody

Western blot analysis of extracts from Jurkat cells, using Ret (Ab-905) antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

RET antibody

RET (Cat. #TA324337) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the RET antibody detected the RET protein (arrow). Mouse IgM 188CT11.2.3 Ascites Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

RET antibody

Western blot analysis of Ret expression in K562 whole cell lysates,The lane on the left is treated with the antigen-specific peptide. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

RET antibody

Western blot analysis of rat (lanes 1 and 3) and mouse (lanes 2 and 4) brain membranes: 1,2. Anti-Ret (extracellular) antibody, (1:200). 3,4. Anti-Ret (extracellular) antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

RET antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY RET (RC214268, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-RET. Mouse IgG1 OTI2G6 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

RET antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of RET positive Human lung tissue using anti-RET mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA805707) Mouse IgG2b OTI5C7 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

RET antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY RET (RC214268, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-RET. Mouse IgG1 OTI2B3 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

RET antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of RET positive Human lung tissue using anti-RET mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA805744) Mouse IgG1 OTI4H3 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

RET antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of RET positive Human lung tissue using anti-RET mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA805745) Mouse IgG1 OTI5D4 Purified Hu P
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

RET antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of RET positive Human lung tissue using anti-RET mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA805761) Mouse IgG1 OTI1G1 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

RET antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of RET positive Human lung tissue using anti-RET mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA805767) Mouse IgG1 OTI5C5 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

RET antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of RET positive Human lung tissue using anti-RET mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA805811) Mouse IgG1 OTI21H4 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

RET antibody

Immunohistochemical staining of paraffin-embedded RET positive Human lung carcinoma tissue using anti-RET mouse monoclonal antibody. (TA805863; heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min) Mouse IgG1 OTI5F2 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

RET antibody

Immunohistochemical staining of paraffin-embedded RET positive Human lung carcinoma tissue using anti-RET mouse monoclonal antibody. (TA805940; heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min) Mouse IgG1 OTI20B8 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

RET antibody

Immunohistochemical staining of paraffin-embedded RET positive Human lung carcinoma tissue using anti-RET mouse monoclonal antibody. (TA805988; heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min) Mouse IgG1 OTI21H5 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

RET antibody

Western blot analysis using RET antibody Cat.-No AM06194SU-N against truncated RET recombinant protein (Lane 1) and RET (aa 658-1063)-hIgGFc transfected CHO-K1 cell lysate (Lane 2). Mouse IgG1 8D10C9 Ascites Hu WB
0.1 ml / €440.00
  Acris Antibodies GmbH

RET antibody

Western blot analysis using RET antibody Cat.-No AM06202SU-N against truncated RET recombinant protein (Lane 1) and RET (aa658-1063)-hIgGFc transfected CHO-K1 cell lysate (Lane 2). Mouse IgG1 6E4C4 Ascites Hu WB
0.1 ml / €400.00
  Acris Antibodies GmbH

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