Reticulon 1 / RTN1 antibody

Principal name

Reticulon 1 / RTN1 antibody

Alternative names for Reticulon 1 / RTN1 antibody

Reticulon-1, RTN1, NSP, Neuroendocrine-specific protein

SwissProt ID

Q04947 (Yeast), Q16799 (Human), Q16799-2, Q64548 (Rat), Q8K0T0 (Mouse), Q9BQ59 (Human)

Gene ID

6252 (RTN1)

Available reactivities

Bov (Bovine), Chk (Chicken), Hu (Human), Ms (Mouse), Rt (Rat), Ze (Zebrafish), African clawed frog, Hst (Hamster), Mky (Monkey), Rb (Rabbit), Por (Porcine), Can (Canine), GP (Guinea Pig), Eq (Equine), Sh (Sheep)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Flow Cytometry (F), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Enzyme Immunoassay (E)

Background of Reticulon 1 / RTN1 antibody

Recently, a novel gene family has been identified and characterized, designated the Reticulons because the proteins encoded by these genes are anchored to the membranes of the endoplasmic reticulum. Reticulon-1 was formerly designated NSP for Neuroendocrine-Specific-Protein, because it is specifically expressed in neural and neuroendocrine tissues. The NSP-gene has been mapped by fluorescence in situ hybridization to human chromosome 14q21-q22. The NSP-gene encodes three overlapping proteins, i.e. Reticulon-1A (NSPA), Reticulon-1B (NSP-B), and Reticulon-1C (NSPC). These proteins were found to be anchored to membranes of the endoplasmic reticulum through their common carboxy-terminal regions. Reticulon-1A is a protein with a molecular weight (MW) of about 135 kDa, which occurs in various isoforms presumably depending on the degree of phosphorylation of serine residues. In lung cancer diagnosis Reticulon-1A appeared to be a reliable marker for the detection of neuroendocrine differentiation, since most of the small cell lung carcinoma (SCLC) and carcinoid tumors showed expression of Reticulon-1A. Reticulon-1B is a phosphoprotein with a MW of 45 kDa and is restricted to the lung cancer cell line NCI-H82. Reticulon-1B is so far not found in human tissues. Reticulon-1C is a protein with a MW of 23 kDa which is not phosphorylated and is found with Reticulon-1A in SCLC (cell lines) and not in non- SCLC (cell cultures). The epitope of MON-162 is located between amino acid residues 338-422 of Reticulon-1A.

General readings

Di (2007) J. Neurochem. 102 (2), 345-353

18 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Reticulon 1 / RTN1 antibody

WB Suggested Anti-RTN1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: 293T cell lysate Rabbit IgG Purified Bov, Can, GP, Hu, Ms, Por, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

Reticulon 1 / RTN1 antibody

WB Suggested Anti-RTN1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: Jurkat cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt, Sh, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

Reticulon 1 / RTN1 (Isoform RTN1-A) antibody

Reticulon 1 / RTN1 Mouse IgG1 MON160 Purified Hst, Hu, Ms, Rt C, F, ICC/IF, P, WB
0.1 mg / €320.00
  Acris Antibodies GmbH

Reticulon 1 / RTN1 (Isoform RTN1-A) antibody

Reticulon 1 / RTN1 Mouse IgG1 MON161 Purified Hst, Hu, Ms, Rt C, F, ICC/IF, P, WB
0.1 mg / €320.00
  Acris Antibodies GmbH

Reticulon 1 / RTN1 (Isoform RTN1-A) antibody

Reticulon 1 / RTN1 Mouse IgG1 MON162 Purified Hst, Hu, Ms, Rt C, ICC/IF, P, WB
0.1 mg / €320.00
  Acris Antibodies GmbH

Reticulon 1 / RTN1 (Isoform RTN1-A/B) antibody

Reticulon 1 / RTN1 Mouse IgG1 RNL-2 Supernatant Hu, Mky, Rb C, F, ICC/IF, P, WB
1 ml / €250.00
  Acris Antibodies GmbH

Reticulon 1 / RTN1 (Isoform RTN1-A/B) antibody

Reticulon 1 / RTN1 Mouse IgG1 RNL-2 Purified Hu, Mky, Rb C, F, ICC/IF, P, WB
0.1 mg / €320.00
  Acris Antibodies GmbH

Reticulon 1 / RTN1 (Isoform RTN1-A/B) antibody

Reticulon 1 / RTN1 Mouse IgG1 RNL-3 Supernatant Hu, Mky, Rb C, F, ICC/IF, P, WB
1 ml / €250.00
  Acris Antibodies GmbH

Reticulon 1 / RTN1 (Isoform RTN1-A/B) antibody

Reticulon 1 / RTN1 Mouse IgG1 RNL-3 Purified Hu, Mky, Rb C, F, ICC/IF, P, WB
0.1 mg / €320.00
  Acris Antibodies GmbH

Reticulon 1 / RTN1 (Isoform RTN1-C) antibody

Immunoblotting of RNL-4 recognizing NSP-C Reticulon 1-C (23 kDa) in extract from neuroblastoma cell line LA-N-5. Mouse IgG1 RNL-4 Supernatant Hu, Por, Rt C, F, ICC/IF, WB
1 ml / €250.00
  Acris Antibodies GmbH

Reticulon 1 / RTN1 (Isoform RTN1-C) antibody

Immunoblotting of RNL-4 recognizing NSP-C Reticulon 1-C (23 kDa) in extract from neuroblastoma cell line LA-N-5. Mouse IgG1 RNL-4 Purified Hu, Por, Rt C, F, ICC/IF, WB
0.1 mg / €320.00
  Acris Antibodies GmbH

Reticulon 1 / RTN1 antibody

Human 293T; WB Suggested Anti-RTN1 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: 293T cell lysate; RTN1 antibody - N-terminal region (ARP49622_P050) in Human 293T cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Chk, Hu, Ms, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

Reticulon 1 / RTN1 antibody

Human Jurkat; WB Suggested Anti-RTN1 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:1562500. Positive Control: Jurkat cell lysate; RTN1 antibody - middle region (ARP49623_P050) in Human Jurkat cells using Western Blot Rabbit Aff - Purified Bov, Can, Chk, Hu, Ms, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Reticulon 1 / RTN1 (transcript variant 1)

Reticulon 1 / RTN1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Reticulon 1 / RTN1 (transcript variant 3)

Reticulon 1 / RTN1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Reticulon 1 / RTN1

Reticulon 1 / RTN1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

Reticulon 1 / RTN1

Reticulon 1 / RTN1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

RTN1 overexpression lysate

RTN1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

18 Item(s)

per page
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