RGMA / RGM antibody

Principal name

RGMA / RGM antibody

Alternative names for RGMA / RGM antibody

Repulsive guidance molecule A, RGM domain family member A

SwissProt ID

Q6PCX7 (Mouse), Q8JG54 (Chick), Q96B86 (Human)

Gene ID

56963 (RGMA), 244058 (Rgma)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Rabbit, Goat, Mouse

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunoprecipitation (IP), Frozen Sections (C), Flow Cytometry (F), Paraffin Sections (P)

Background of RGMA / RGM antibody

The repulsive guidance molecule (RGM) family of proteins are important in the guidance of growth cones of developing neurons. They are repulsive for a group of axons, those from the temporal half of the retina. RGM have been implicated in both axonal guidance and neural tube closure, but unlike ephrins, semaphorins, netrins and slits, no receptor mechanism for RGM activation has been defined. Dorsal root ganglion axons do not respond to RGM but neogenin (a netrin-binding protein which can function as an RGM receptor) expression can spur RGM responsiveness. The RGM proteins are attached to the membrane by a GPI-anchor. Two members of this family, RGMa and RGMb, are expressed in the nervous system. RGMc, also known as hemojuvelin, is a part of the signaling pathway activating hepcidin and works together with hepcidin to restrict iron absorption in the gut. Defects in the gene encoding for RGMc cause the autosomal recessive disorder juvenile hemochromatosis (JH).

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

RGMA / RGM antibody

Host: Rabbit; Target Name: Rgma; Sample Tissue: Mouse Heart lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

RGMA / RGM antibody

RGMA / RGM Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

RGMA / RGM antibody

RGMA / RGM Mouse IgG3 6D7 Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

RGMA / RGM antibody

RGMA / RGM Goat IgG Aff - Purified Ms C, E, F
0.1 mg / €450.00
  Neuromics Antibodies

RGMA / RGM antibody

RGMA / RGM Rabbit Purified Hu C, P, WB
0.1 ml / €400.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

RGMA / RGM

RGMA / RGM Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

RGMA / RGM

RGMA / RGM Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

RGMA / RGM

RGMA / RGM Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

RGMA overexpression lysate

RGMA overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

RGMA overexpression lysate

RGMA overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Lysates (Overexpressed)

Catalog No.    

RGMA overexpression lysate

RGMA overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

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