RGS18 antibody

Principal name

RGS18 antibody

Alternative names for RGS18 antibody

RGS13, Regulator of G-protein signaling 18

SwissProt ID

Q4L0E8 (Rat), Q99PG4 (Mouse), Q9NS28 (Human)

Gene ID

64407 (RGS18), 64214 (Rgs18)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit, Goat

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of RGS18 antibody

RGS18 is a member of the regulator of G-protein signaling family. This protein is contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.This gene encodes a member of the regulator of G-protein signaling family. This protein is contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

General readings

1. Park IK, Klug CA, Li K, Jerabek L, Li L, Nanamori M, Neubig RR, Hood L, Weissman IL, Clarke MF.
Molecular cloning and characterization of a novel regulator of G-protein signaling from mouse hematopoietic stem cells.
J Biol Chem. 2001 Jan 12;276(2):915-23. PMID: 11042171

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

RGS18 (C-term) antibody

  Goat Anti-RGS18 Antibody  
TA305725 (1ug/ml) staining of Human Peripheral Blood Mononucleocytes lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat IgG Aff - Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

RGS18 antibody

  Rabbit Polyclonal anti-RGS18 antibody  
WB Suggested Anti-RGS18 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: HepG2 cell lysate Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

RGS18 antibody

  Rabbit Polyclonal anti-Rgs18 antibody  
WB Suggested Anti-Rgs18 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: Mouse Lung Rabbit IgG Purified Ms WB
50 µg / €325.00
  OriGene Technologies, Inc.

RGS18 antibody

  Rabbit Polyclonal RGS18 Antibody  
Western Blot: RGS18 Antibody [TA336471] - Analysis of RGS18 in human lung lysate using this antibody at a dilution of 2 ug/ml. Rabbit Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

RGS18 antibody

  Rabbit Polyclonal RGS18 Antibody  
Western Blot: RGS18 Antibody [TA336970] - Western blot analysis of RGS18 in 1) transfected 293T cells and 2) untransfected 293T cells using TA336970 at 1:500. Rabbit Purified Hu ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CRISPR

Catalog No. Species Donor Vector  

RGS18 - human gene knockout kit via CRISPR

RGS18 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

RGS18 - human gene knockout kit via CRISPR

RGS18 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

RGS18 - human gene knockout kit via CRISPR

RGS18 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

RGS18 - human gene knockout kit via CRISPR

RGS18 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Rgs18 - mouse gene knockout kit via CRISPR

Rgs18 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Rgs18 - mouse gene knockout kit via CRISPR

Rgs18 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Rgs18 - mouse gene knockout kit via CRISPR

Rgs18 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Rgs18 - mouse gene knockout kit via CRISPR

Rgs18 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

RGS18 (full length, N-term HIS tag)

  Recombinant protein of human regulator of G-protein signaling 18 (RGS18), full length, with N-terminal HIS tag, expressed in E.Coli, 50ug  
RGS18 Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
50 µg / €199.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

RGS18 overexpression lysate

RGS18 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, RGS18 (mGFP-tagged) - Human regulator of G-protein signaling 18 (RGS18), 200 uL, >10^7 TU/mL

Lenti ORF particles, RGS18 (mGFP-tagged) - Human regulator of G-protein signaling 18 (RGS18), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, RGS18 (Myc-DDK tagged) - Human regulator of G-protein signaling 18 (RGS18) , 200 uL, >10^7 TU/mL

Lenti ORF particles, RGS18 (Myc-DDK tagged) - Human regulator of G-protein signaling 18 (RGS18) , 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

17 Item(s)

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