RGS22 antibody

Principal name

RGS22 antibody

Alternative names for RGS22 antibody

Regulator of G-protein signaling 22

SwissProt ID

Q8NE09 (Human)

Gene ID

26166 (RGS22)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Eq (Equine), Por (Porcine)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Enzyme Immunoassay (E), Paraffin Sections (P)

Background of RGS22 antibody

Regulator of G-protein signaling (RGS) proteins contain an 120 amino acid conserved domain, termed the RGS domain, that acts as a GTPase-activating protein that acts to reduce the signal transmitted by the receptor-activated G-alpha subunit (1,2). RGS22 is a recently identified member of this family that localizes to the testis and can interact with guanine nucleotide binding proteins alpha 11, 12, and 13 (GNA11, GNA12, and GNA13). While RGS22 has been postulated to play a role in spermiogenesis in the testis, it is also expressed in several cancer cell lines with an epithelial origin and associated with cancer metastasis. Its overexpression in a highly metastatic cancer causes a decrease in cell migration and a reduction of the invasive potential of the cells, suggesting that RGS22 may be a potential prognostic biomarker for metastasis.

General readings

Hu Y, Xing J, Chen L, et al. RGS22, a novel testis-specific regulator of G-protein signaling involved in human and mouse spermiogenesis along with GNA12/13 subunits. Biol. Reprod. 2008; 79:1021-9.

9 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

RGS22 (N-term) antibody

  Rabbit Polyclonal RGS22 Antibody  
Western blot analysis of RGS22 in Jurkat cell lysate with RGS22 antibody at (A) 1 and (B) 2 ug/mL. Rabbit IgG Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

RGS22 antibody

  Rabbit Polyclonal Anti-RGS22 Antibody  
WB Suggested Anti-RGS22 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: Transfected 293T Rabbit IgG Purified Bov, Eq, Hu, Por, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

RGS22 antibody

  Rabbit Polyclonal Anti-RGS22 Antibody  
Gel: 6%SDS-PAGE, Lysate: 40 ug, Lane 1-2: Hela cells, hepg2 cells, Primary antibody: (RGS22 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds Rabbit IgG Purified Hu E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CRISPR

Catalog No. Species Donor Vector  

RGS22 - human gene knockout kit via CRISPR

RGS22 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

RGS22 - human gene knockout kit via CRISPR

RGS22 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

RGS22 - human gene knockout kit via CRISPR

RGS22 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

RGS22 - human gene knockout kit via CRISPR

RGS22 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, RGS22 (mGFP-tagged)-Human regulator of G-protein signaling 22 (RGS22), 200 uL, >10^7 TU/mL

Lenti ORF particles, RGS22 (mGFP-tagged)-Human regulator of G-protein signaling 22 (RGS22), 200 uL, >10^7 TU/mL  
200 µl / €1,320.00
  OriGene Technologies, Inc.

Lenti ORF particles, RGS22 (Myc-DDK-tagged)-Human regulator of G-protein signaling 22 (RGS22), 200 uL, >10^7 TU/mL

Lenti ORF particles, RGS22 (Myc-DDK-tagged)-Human regulator of G-protein signaling 22 (RGS22), 200 uL, >10^7 TU/mL  
200 µl / €1,180.00
  OriGene Technologies, Inc.

9 Item(s)

per page
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