RHBDD3 antibody

Principal name

RHBDD3 antibody

Alternative names for RHBDD3 antibody

C22orf3, Rhomboid domain-containing protein 3

SwissProt ID

Q642B3 (Rat), Q8BP97 (Mouse), Q9Y3P4 (Human)

Gene ID

25807 (RHBDD3)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts


Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P)

Background of RHBDD3 antibody

The Rhomboid family of proteins is made up of several widely conserved polytopic membrane serine proteases that play roles in growth and development. RHBDD3 was initially identified as a novel pituitary tumor apoptosis gene (PTAG) whose expression was reduced in certain pituitary adenomas. Overexpression of RHBDD3 in AtT20 cells showed an increase in apoptotic activity and caspase activation in response to bromocriptine, and apoptosis-inducing dopamine D2 analog, suggesting that reactivation of RHBDD3 in tumors may be a therapeutically useful tool. Later experiments also showed that RHBDD3 expression is also reduced in several primary colorectal tumors, indicating that loss of RHBDD3 contributes to a blunted apoptotic response and probably predisposes cells towards malignant transformation.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

RHBDD3 antibody

Western blot analysis of RHBDD3 in rat lung tissue lysate with RHBDD3 antibody at 1 µg/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

RHBDD3 antibody

Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Purified Hu, Ms, Rt E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

RHBDD3 Control Peptide

50 µg / €160.00
  Acris Antibodies GmbH

3 Item(s)

per page
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