RHEB antibody

Principal name

RHEB antibody

Alternative names for RHEB antibody

RHEB2, GTP-binding protein Rheb, Ras homolog enriched in brain

SwissProt ID

P25378 (Yeast), Q15382 (Human), Q56JV3 (Bovin), Q62639 (Rat), Q921J2 (Mouse), Q9VND8 (Drome)

Gene ID

6009 (RHEB), 19744 (Rheb), 26954

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), Sh (Sheep), Ze (Zebrafish)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), ELISA (detection) (E(detection)), Paraffin Sections (P), Immunoprecipitation (IP)

Background of RHEB antibody

Rheb (Ras homolog enriched in brain) is an evolutionarily conserved member of the Ras family of small GTP-binding proteins originally found to be rapidly induced by synaptic activity in the hippocampus following seizure (1). While it is expressed at relatively high levels in the brain, Rheb is widely expressed in other tissues and may be induced by growth factor stimulation. Similar to other family members, Rheb triggers activation of the Raf-MEK-MAPK pathway (2). Biochemical and genetic studies demon-strate that Rheb has an important role in regulating the insulin/Target of rapamycin (TOR) signaling pathway (3-5). TOR is a serine/threonine protein kinase that acts as a sensor for ATP and amino acids, balancing the availability of nutrients with protein translation and cell growth. A dimeric protein complex termed TSC1/TSC2 indirectly inhibits TOR activity by inhibiting Rheb via the GAP activity of TSC2 (3).

General readings

Tabancay AP Jr., et al. (2003).J Biol Chem. 10;278(41):39921-30.

19 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

RHEB (N-term) antibody

  Rabbit Polyclonal Rheb Antibody  
Western blot analysis of Rheb in rat heart cell lysate with Rheb antibody at (A) 2 and (B) 4 µg/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €371.00
  OriGene Technologies, Inc.

RHEB (Center) antibody

  Rabbit Polyclonal Rheb Antibody  
Western blot analysis of Rheb in mouse brain cell lysate with Rheb antibody at (A) 1, (B) 2, and (C) 4 ug/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €371.00
  OriGene Technologies, Inc.

RHEB antibody

  Anti-RHEB Rabbit Polyclonal Antibody  
Predicted cell location: Cytoplasm. Positive control: Human colon and ovarian cancer tissue. Recommended dilution: 1/50-200 . The image on the left is immunohistochemistry of paraffin-embedded human colon cancer tissue using RHEB antibody at dilution 1/30, on the right is treated with the synthetic peptide. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €335.00
  OriGene Technologies, Inc.

RHEB antibody

  Anti-RHEB Rabbit Polyclonal Antibody  
Predicted cell location: Cytoplasm. Positive control: Human brain and ovarian cancer tissue. Recommended dilution: 1/50-200  The image on the left is immunohistochemistry of paraffin-embedded human brain tissue using RHEB antibody at dilution 1/25, on the right is treated with the synthetic peptide. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €335.00
  OriGene Technologies, Inc.

RHEB antibody

  RHEB Rabbit Polyclonal Antibody  
Western blot analysis of brian cell and Hela cell lysate using RHEB antibody. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €335.00
  OriGene Technologies, Inc.

RHEB antibody

  Rabbit polyclonal Anti-RHEB Antibody  
WB Suggested Anti-RHEB Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: Human Muscle Rabbit IgG Purified Bov, Can, Eq, Hu, Ms, Rt, Sh, Ze WB
50 µg / €360.00
  OriGene Technologies, Inc.

RHEB antibody

  Rabbit Polyclonal Anti-RHEB Antibody  
RHEB Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €335.00
  OriGene Technologies, Inc.

RHEB antibody

  Rabbit Polyclonal Anti-RHEB Antibody  
RHEB Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €335.00
  OriGene Technologies, Inc.

RHEB antibody

Figure 1. Formalin-Fixed Paraffin-Embedded (FFPE) on Brain, cortex. Rabbit Aff - Purified Hu, Ms, Rt P, WB
50 µg / €380.00
  OriGene Technologies GmbH

RHEB (C-term) antibody

Formalin fixed, paraffin embedded human skeletal muscle stained with RHEB Antibody (C-term) Cat.-No AP53656PU-N followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RHEB Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. Rabbit Ig Purified Bov, Hu, Ms, Rt P, WB
0.4 ml / €370.00
  OriGene Technologies GmbH

RHEB antibody

Immunohistochemical staining of mouse brain with Rabbit anti Human Rheb (SP2154P) Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 mg / €340.00
  OriGene Technologies GmbH

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

RHEB

  Recombinant protein of human Ras homolog enriched in brain (RHEB)  
RHEB Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

RHEB (1-181, T7-tag)

RHEB Human Purified > 95 % by SDS-PAGE E. coli
0.5 mg / €540.00
  OriGene Technologies GmbH

RHEB (1-181, T7-tag)

RHEB Human Purified > 95 % by SDS-PAGE E. coli
0.1 mg / €230.00
  OriGene Technologies GmbH

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, RHEB (mGFP-tagged) - Human Ras homolog enriched in brain (RHEB), 200 uL, >10^7 TU/mL

Lenti ORF particles, RHEB (mGFP-tagged) - Human Ras homolog enriched in brain (RHEB), 200 uL, >10^7 TU/mL  
200 µl / €907.00
  OriGene Technologies, Inc.

Lenti ORF particles, RHEB (Myc-DDK tagged) - Human Ras homolog enriched in brain (RHEB) , 200 uL, >10^7 TU/mL

Lenti ORF particles, RHEB (Myc-DDK tagged) - Human Ras homolog enriched in brain (RHEB) , 200 uL, >10^7 TU/mL  
200 µl / €804.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Rheb (GFP-tagged) - Mouse Ras homolog enriched in brain (Rheb), 200 uL, >10^7 TU/mL

Lenti ORF particles, Rheb (GFP-tagged) - Mouse Ras homolog enriched in brain (Rheb), 200 uL, >10^7 TU/mL  
200 µl / €907.00
  OriGene Technologies, Inc.

Lenti ORF particles, Rheb (Myc-DDK-tagged) - Mouse Ras homolog enriched in brain (Rheb), 200 uL, >10^7 TU/mL

Lenti ORF particles, Rheb (Myc-DDK-tagged) - Mouse Ras homolog enriched in brain (Rheb), 200 uL, >10^7 TU/mL  
200 µl / €804.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Rheb (GFP-tagged ORF) - Rat Ras homolog enriched in brain (Rheb), 200 uL, >10^7 TU/mL

Lenti ORF particles, Rheb (GFP-tagged ORF) - Rat Ras homolog enriched in brain (Rheb), 200 uL, >10^7 TU/mL  
200 µl / €907.00
  OriGene Technologies, Inc.

19 Item(s)

per page
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