Rhombotin-2 antibody

Principal name

Rhombotin-2 antibody

Alternative names for Rhombotin-2 antibody

LMO2, RBTN2, RBTNL1, RHOM2, TTG2, Rhombotin2, LIM domain only protein 2, Cysteine-rich protein TTG-2, T-cell translocation protein 2

SwissProt ID

P25791 (Human), P25801 (Mouse), Q1LZ94 (Bovin)

Gene ID

4005 (LMO2), 16909 (Lmo2)

Available reactivities

Hu (Human), Bov (Bovine), Ms (Mouse), Rt (Rat), Chk (Chicken), African clawed frog

Available hosts

Mouse, Sheep, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Paraffin Sections (P), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Flow Cytometry (F), ChIP assay (ChIP)

Background of Rhombotin-2 antibody

LMO2 (LIM-only protein 2) is a nuclear transcriptiol regulator essential for normal blood cell development and it exerts its effects by mediating protein-protein interactions as well as by nucleating multicomponent transcriptiol complexes. LMO2 interacts with LDB1 (LIM domain binding protein 1) through the tandem LIM domains of LMO2 and LID (LIM interaction domain) of LDB1. LMO2 also interacts with bHlH proteins TAL1/SCL, BEX2 and KDM5A, and form complex with TAL1/SCL. It functions with TAL1/SCL in the regulation of RBCs development and with LDB1 to maintain erythroid precursors in immature state. LMO2 has been associated with the maintence of hematopoietic stem cells, RBCs differentiation, and angiogenesis in both normal development as well as during carcinogenesis. Disruption of LMO2 in mice causes death in midway through embryonic development as they do not develop RBCs. Excessive expression of LMO2 in T-cells, through either chromosomal translocations or retroviral insertion of gene therapy vectors, as well as transgenic overexpression of LMO2 in mouse model leads to the onset of T-cell acute lymphoblastic leukemia (T-ALL).

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Rhombotin-2 antibody

  LMO2 mouse monoclonal antibody, clone OTI1G10 (formerly 1G10)  
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-LMO2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA506132) Mouse IgG1 OTI1G10 Purified Hu P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

Rhombotin-2 antibody

  LMO2 mouse monoclonal antibody, clone OTI1D7 (formerly 1D7)  
Immunohistochemical staining of paraffin-embedded Carcinoma of Human pancreas tissue using anti-LMO2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA506133) Mouse IgG1 OTI1D7 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Rhombotin-2 antibody

  LMO2 mouse monoclonal antibody, clone OTI1C8 (formerly 1C8)  
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-LMO2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA506139) Mouse IgG1 OTI1C8 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Rhombotin-2 antibody

  Mouse Monoclonal LMO2 Antibody (1A9-3B11)  
Western Blot: LMO2 Antibody (1A9-3B11) - Detection of LMO2 in Ramos cell lysate Mouse IgG1 1A9-3B11 Purified Hu C, ICC/IF, IP, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Rhombotin-2 antibody

  Mouse Anti-Human LMO2 Purified (25 ug)  
Immunohistochemistry of human tonsil tissue at a 1:1000 dilution of Anti-Human LMO2 Purified followed by Anti-Mouse IgG Biotin and avidin HRP and high (right) magnifications are shown. Mouse 1A9-3B11 Purified Hu P
25 µg / €130.00
  OriGene Technologies, Inc.

Rhombotin-2 antibody

  Rabbit Polyclonal anti-LMO2 Antibody  
Host: Rabbit; Target Name: LMO2; Sample Tissue: Ovary Tumor lysates; Antibody Dilution: 1.0ug/ml Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

Rhombotin-2 antibody

  Rabbit Polyclonal Anti-LMO2 Antibody  
WB Suggested Anti-LMO2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:1562500; Positive Control: Human kidney Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

Rhombotin-2 antibody

  Rabbit Polyclonal LMO2 Antibody  
SDS-Page: LMO2 Antibody [TA336557] - Detection of LMO2 in Ramos whole cell lysate using TA336557. Rabbit Purified Bov, Hu, Ms, Rt ChIP, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Rhombotin-2 antibody

  LMO2 mouse monoclonal antibody, clone OTI2D7 (formerly 2D7)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY LMO2 (RC205376, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-LMO2. Mouse IgG1 OTI2D7 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Rhombotin-2 antibody

Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE) Mouse IgG1 1A9-3B11 Aff - Purified Hu P, WB
50 µg / €470.00
  Acris Antibodies GmbH

Rhombotin-2 antibody

Rhombotin-2 Sheep IgG Purified Hu WB
0.25 mg / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

LMO2 - human gene knockout kit via CRISPR

LMO2 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

LMO2 - human gene knockout kit via CRISPR

LMO2 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

LMO2 - human gene knockout kit via CRISPR

LMO2 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

LMO2 - human gene knockout kit via CRISPR

LMO2 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lmo2 - mouse gene knockout kit via CRISPR

Lmo2 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Lmo2 - mouse gene knockout kit via CRISPR

Lmo2 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lmo2 - mouse gene knockout kit via CRISPR

Lmo2 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lmo2 - mouse gene knockout kit via CRISPR

Lmo2 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Rhombotin-2 (transcript variant 1)

  Recombinant protein of human LIM domain only 2 (rhombotin-like 1) (LMO2), transcript variant 1  
Rhombotin-2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

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