RICIN / RCA60 antibody

Principal name

RICIN / RCA60 antibody

Alternative names for RICIN / RCA60 antibody

RCAII, Ricinus communis toxin, Castor bean toxin

SwissProt ID

P02879 (Ricco)

Gene ID

8287993 (B9T8T0)

Available reactivities

Ricinus communis, Pl (Plant)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of RICIN / RCA60 antibody

Ricinus communis agglutinin 60(RCA60) is an extremely toxic glycoprotein consisting of two disulfide-linked chains of about 28,000 daltons and 32,000 daltons, termed A and B chain, respectively. The B chain can bind to cell surfaces via galactose or N-acetylgalactosamine residues of membrane glycoconjugates and facilitates the transport of the lectin into the cell. The A chain has an enzyme activity which can catalytically block protein synthesis and is so toxic that only a single molecule of A chain is required to kill a cell. Alone, the A chain is incapable of entering the cell and is thus not toxic. The A chain can be separated from the B chain and then linked by a cleavable disulfide bond to other proteins, such as antibodies. These antibody-toxin hybrid molecules can be used to kill specific cells with the appropriate antigenic determinant exposed, such as tumor markers on surfaces of malignant cells.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

RICIN / RCA60 antibody

RICIN / RCA60 Mouse IgG1 322-13236 Purified E
1 mg / €590.00
  Acris Antibodies GmbH

RICIN / RCA60 A-chain antibody

RICIN / RCA60 Rabbit Purified E
1 mg / €690.00
  Acris Antibodies GmbH

RICIN / RCA60 A-chain (+ RCA120) antibody

RICIN / RCA60 Mouse IgM CP23 E, WB
0.2 mg / €640.00
  Abnova Taiwan Corp.

RICIN / RCA60 A-chain antibody

RICIN / RCA60 Mouse IgM CP23 Purified Ricinus communis E
1 mg / €440.00
  HyTest Ltd.

RICIN / RCA60 A-chain antibody

RICIN / RCA60 Mouse IgG2a CP37 Purified Ricinus communis E, WB
1 mg / €440.00
  HyTest Ltd.

RICIN / RCA60 A-chain antibody

RICIN / RCA60 Mouse IgG1 CP75 Purified Ricinus communis E, WB
1 mg / €440.00
  HyTest Ltd.

RICIN / RCA60 A-chain (+ RCA120) antibody

RICIN / RCA60 Mouse IgG1 RA999 Purified Ricinus communis E, WB
1 mg / €440.00
  HyTest Ltd.

RICIN / RCA60 B-chain antibody

RICIN / RCA60 Mouse IgG1 RB999 Purified Ricinus communis WB
1 mg / €440.00
  HyTest Ltd.

RICIN / RCA60 A-chain (+ RCA120) antibody

RICIN / RCA60 Mouse IgG2a CP37 Purified Pl E, WB
0.5 mg / €400.00
  Novus Biologicals Inc.

RICIN / RCA60 A-chain (+ RCA120) antibody

RICIN / RCA60 Mouse IgG1 CP75 Purified Pl E, WB
0.5 mg / €400.00
  Novus Biologicals Inc.

10 Item(s)

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