RNASE2 antibody

Principal name

RNASE2 antibody

Alternative names for RNASE2 antibody

EDN, RNS2, Ribonuclease 2, Non-secretory ribonuclease,Ribonuclease US, Eosinophil-derived neurotoxin, RNase UpI-2

SwissProt ID

O35291 (Mouse), P10153 (Human), P80551 (Pig)

Gene ID

6036 (RNASE2)

Available reactivities

Hu (Human)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Paraffin Sections (P)

Background of RNASE2 antibody

Upon activation, eosinophils secrete several cationic proteins including major basic protein (MBP), eosinophil cationic protein (ECP), eosinophil peroxidase (EPO) and eosinophil-derived neurotoxin (EDN). EDN, also called eosinophil protein X (EPX) is a glycosylated single-chain protein with a molecular weight 18-21 kDa and is a member of the ribonuclease A superfamily along with ECP. Although EDN has high sequence homology to ECP, EDN has 100-fold greater ribonuclease activity than ECP and neurotoxicity but not cytotoxicity. Eosinophil and its activation have been found to play an important role in inflammatory processes in allergic diseases. EDN can be a marker of eosinophil activation and degranulation.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

RNASE2 antibody

Western blot analysis of EDN expression in human leukocyte using AM26581AF-N. Mouse IgG2a 3H8 Azide Free Hu WB
0.1 mg / €380.00
  Acris Antibodies GmbH

RNASE2 antibody

RNASE2 Rabbit Serum E
0.1 ml / €500.00
  Acris Antibodies GmbH

RNASE2 antibody

RNASE2 Rabbit Serum E
20 µl / €170.00
  Acris Antibodies GmbH

RNASE2 antibody

RNASE2 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

RNASE2 antibody

Western Blot analysis of RNASE2 expression in transfected 293T cell line (H00006036-T01) by RNASE2 MaxPab polyclonal antibody.

Lane1:RNASE2 transfected lysate(17.71 KDa).
Lane2:Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

RNASE2 antibody

RNASE2 MaxPab rabbit polyclonal antibody. Western Blot analysis of RNASE2 expression in human spleen. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

RNASE2 antibody

Immunohistochemistry-Paraffin: Eosinophil derived neurotoxin Antibody [NBP1-91872] Immunohistochemical staining of human bone marrow shows strong cytoplasmic positivity in a subset of cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

RNASE2

RNASE2 Human
2 µg / €300.00
  Abnova Taiwan Corp.

RNASE2

RNASE2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

RNASE2

RNASE2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

RNASE2 293T Cell Transient Overexpression Lysate(Denatured)

RNASE2 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

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