RNASEH2A antibody

Principal name

RNASEH2A antibody

Alternative names for RNASEH2A antibody

Ribonuclease H2 subunit A, RNase H2 subunit A, RNAse H2A, RNase HI large subunit, RNASEHI, RNHIA, AGS4, Ribonuclease HI subunit A, Ribonuclease HI large subunit, Aicardi-Goutieres syndrome 4 protein

SwissProt ID

O75792 (Human), P53942 (Yeast), Q10236 (Schpo), Q2TBT5 (Bovin), Q5U209 (Rat), Q9CWY8 (Mouse), Q9SEZ6 (Arath), Q9U6P6 (Caeel), Q9VPP5 (Drome)

Gene ID

10535 (RNASEH2A)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Ze (Zebrafish), African clawed frog, Eq (Equine), Gt (Goat), Por (Porcine), Ye (Yeast)

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Immunoprecipitation (IP), Paraffin Sections (P), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), ELISA (detection) (E(detection))

Background of RNASEH2A antibody

Ribonucleases (RNAses) H are enzymes that hydrolyze the RNA strands of RNA/DNA hybrids. The major role of these enzymes is to remove the RNA strand from the RNA/DNA hybrids that form during DNA replication and repair. RNAse H2 is made up of three subunits; all three are required for RNAse activity. Recent evidence has demonstrated that mutations in RNAse H2A or any of the other subunits result in Aicardi-Goutieres syndrome (AGS), a neurological disorder with similar symptoms to viral brain infections including high levels of IFN-alpha in the cerebral spinal fluid. Similar conditions are observed with mutations in TREX1, a single-stranded DNA exonuclease, suggesting that RNAse H2 and TREX1 may have similar roles, and that mutations in any of these genes lead to an accumulation of intracellular nucleic acids, triggering an inflammatory response through activation of the innate immune system.

General readings

Frank P., et al. (1998) Proc Natl Acad Sci USA. 95:12872-12877.Bayliss C D., et al. (2005) Nucleic Acads Res. 33:400-408.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

RNASEH2A antibody

Western blot analysis of RNAse H2A in HeLa cell lysate with RNAse H2A antibody at 1 ug/mL. Rabbit IgG Aff - Purified Hu, Ms, Rt ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

RNASEH2A antibody

Immunofluorescence of purified MaxPab antibody to RNASEH2A on HeLa cell. [antibody concentration 10 ug/ml] Mouse Purified Hu E(detection), ICC/IF, WB
50 µg / €370.00
  Abnova Taiwan Corp.

RNASEH2A antibody

WB Suggested Anti-RNASEH2A Antibody Titration: 0.2-1 ug/ml; Positive Control: Jurkat cell lysateRNASEH2A is supported by BioGPS gene expression data to be expressed in Jurkat Rabbit IgG Purified Hu P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

RNASEH2A antibody

WB Suggested Anti-RNASEH2A Antibody Titration: 1.25 ug/ml; Positive Control: Jurkat cell lysateRNASEH2A is supported by BioGPS gene expression data to be expressed in Jurkat Rabbit IgG Purified Bov, Can, Eq, Gt, Hu, Ms, Por, Rt, Ye, Ze P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

RNASEH2A Control Peptide

RNASEH2A
50 µg / €160.00
  Acris Antibodies GmbH

RNASEH2A antibody

RNASEH2A Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

RNASEH2A antibody

Western Blot analysis of RNASEH2A expression in transfected 293T cell line (H00010535-T02) by RNASEH2A MaxPab polyclonal antibody.

Lane 1: RNASEH2A transfected lysate(33.40 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

RNASEH2A antibody

Western blot analysis of RNASEH2A over-expressed 293 cell line, cotransfected with RNASEH2A Validated Chimera RNAi ( Cat # H00010535-R01V ) (Lane 2) or non-transfected control (Lane 1). Blot probed with RNASEH2A monoclonal antibody (M01), clone 3G5-F5 (Cat # H00010535-M01 ). GAPDH ( 36.1 kDa ) used as specificity and loading control. Mouse IgG1 3G5-F5 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

RNASEH2A antibody

Human Kidney; Rabbit Anti-RNASEH2A Antibody. Catalog Number: ARP40646. Paraffin Embedded Tissue: Human Kidney. Cellular Data: Epithelial cells of renal tubule. Antibody Concentration: 4.0-8.0 ug/ml. Magnification: 400X; RNASEH2A antibody - C-terminal region (ARP40646_P050) in Human Kidney cells using Immunohistochemistry Rabbit Aff - Purified Hu P, WB
50 µg / €350.00
  AVIVA Systems Biology

RNASEH2A antibody

Human Kidney; Rabbit Anti-RNASEH2A Antibody. Catalog Number: ARP40647. Paraffin Embedded Tissue: Human Kidney. Cellular Data: Epithelial cells of renal tubule. Antibody Concentration: 4.0-8.0 ug/ml. Magnification: 400X; RNASEH2A antibody - middle region (ARP40647_T100) in Human Kidney cells using Immunohistochemistry Rabbit Aff - Purified African clawed frog, Bov, Can, Hu, Ms, Rt, Ze P, WB
0.1 mg / €310.00
  AVIVA Systems Biology

RNASEH2A antibody

Western Blot: RNASEH2A Antibody [NBP1-58234] - This Anti-RNASEH2A antibody was used in Western Blot of Jurkat tissue lysate at a concentration of 0.25ug/ml. Rabbit Aff - Purified Hu P, WB
50 µg / €440.00
  Novus Biologicals Inc.

RNASEH2A antibody

Western Blot: RNASEH2A Antibody [NBP1-58235] - This Anti-RNASEH2A antibody was used in Western Blot of Jurkat tissue lysate at a concentration of 1.25ug/ml. Rabbit Purified Hu, Ze P, WB
0.1 mg / €360.00
  Novus Biologicals Inc.

RNASEH2A antibody

Immunocytochemistry: RNASEH2A Antibody [NBP1-76981] - HeLa cells with RNAse H2A antibody at 2 ug/mL. _x000d_ Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

RNASEH2A antibody

Immunohistochemistry-Paraffin: RNASEH2A Antibody [NBP1-89201] - Immunohistochemical staining of human pancreas shows strong cytoplasmic positivity in exocrine glandular cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

RNASEH2A

RNASEH2A Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

RNASEH2A (1-299, His-tag)

RNASEH2A Human Purified > 85 % by SDS - PAGE E. coli
0.5 mg / €940.00
  Acris Antibodies GmbH

RNASEH2A (1-299, His-tag)

RNASEH2A Human Purified > 85 % by SDS - PAGE E. coli
0.1 mg / €370.00
  Acris Antibodies GmbH

RNASEH2A

RNASEH2A Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

RNASEH2A

RNASEH2A Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Antibody Pairs

Catalog No.    

RNASEH2A (Human) Matched Antibody Pair

RNASEH2A (Human) Matched Antibody Pair  
1 set / €710.00
  Abnova Taiwan Corp.

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