RNASEN antibody

Principal name

RNASEN antibody

Alternative names for RNASEN antibody

Ribonuclease 3, Ribonuclease III, RNase III, RN3, RNASE3L, Drosha

SwissProt ID

O01326 (Caeel), Q9NRR4 (Human)

Gene ID

29102 (DROSHA)

Available reactivities

Hu (Human), Can (Canine), Ms (Mouse), Rt (Rat), Bov (Bovine), Chk (Chicken), Mky (Monkey), Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Goat, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunoprecipitation (IP), Frozen Sections (C)

Background of RNASEN antibody

RNASEN is a ribonuclease III double-stranded (ds) RNA-specific endoribonuclease that is involved in the initial step of microRNA (miRNA) biogenesis. Component of the microprocessor complex that is required to process primary miRNA transcripts (pri-miRNAs) to release precursor miRNA (pre-miRNA) in the nucleus. Within the microprocessor complex, RNASEN/DROSHA cleaves the 3' and 5' strands of a stem-loop in pri-miRNAs (processing center 11 bp from the dsRNA-ssRNA junction) to release hairpin-shaped pre-miRNAs that are subsequently cut by the cytoplasmic DICER to generate mature miRNAs. RNASEN is also involved in pre-rRNA processing. RNASEN cleaves double-strand RNA and does not cleave single-strand RNA. RNASEN is involved in the formation of GW bodies.Members of the ribonuclease III superfamily of double-stranded (ds) RNA-specific endoribonucleases participate in diverse RNA maturation and decay pathways in eukaryotic and prokaryotic cells (Fortin et al., 2002 [PubMed 12191433]). The RNase III Drosha is the core nuclease that executes the initiation step of microRNA (miRNA) processing in the nucleus (Lee et al., 2003 [PubMed 14508493]).[supplied by OMIM].

General readings

Thomson JM, Newman M, Parker JS, Morin-Kensicki EM, Wright T, Hammond SM.
Extensive post-transcriptional regulation of microRNAs and its implications for cancer.
Genes Dev. 2006 Aug 15;20(16):2202-7. Epub 2006 Aug 1.
PMID: 16882971

14 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

RNASEN antibody

TA303168 (0.5µg/ml) staining of Human Liver lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Can, Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

RNASEN antibody

WB Suggested Anti-RNASEN Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: Human Spleen Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

RNASEN antibody

WB using the antibody against DROSHA diluted 1:1,000 in TBS-Tween containing 5% skimmed milk. The position of the protein of interest (expected size 159 kDa) is indicated on the right; the marker (in kDa) is shown on the left. Rabbit IgG Purified Ms E
0.1 ml / €325.00
  OriGene Technologies, Inc.

RNASEN antibody

RNASEN Rabbit Serum Hu C, E, WB
0.2 ml / €400.00
  Acris Antibodies GmbH

RNASEN antibody

Human Spleen; WB Suggested Anti-RNASEN Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: Human Spleen; RNASEN antibody - middle region (ARP40736_P050) in Human Spleen cells using Western Blot Rabbit Aff - Purified Bov, Chk, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

RNASEN antibody

Western blot analysis of DROSHA expression in Jurkat (A); HeLa (B); NIH3T3 (C); PC12 (D) whole cell lysates. Rabbit Aff - Purified Hu, Mky, Ms, Rt WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

RNASEN antibody

Western blot analysis of DROSHA expression in Jurkat (A); HeLa (B); NIH3T3 (C); PC12 (D) whole cell lysates. Rabbit Aff - Purified Hu, Mky, Ms, Rt WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

RNASEN antibody

Western blot analysis of DROSHA expression in Jurkat (A); HeLa (B); NIH3T3 (C); PC12 (D) whole cell lysates. Rabbit Aff - Purified Hu, Mky, Ms, Rt WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

RNASEN antibody

Western Blot: Drosha Antibody [NB100-55410] - NB100-55410 (0.5ug/ml) staining of Human Liver lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat IgG Aff - Purified Hu E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

RNASEN antibody

Immunohistochemistry-Paraffin: Drosha Antibody [NBP1-03349] - Please see notes section Rabbit IgG Aff - Purified Hu IP, P, WB
0.1 ml / €440.00
  Novus Biologicals Inc.

RNASEN antibody

Western Blot: Drosha Antibody [NBP1-57139] - This Anti-RNASEN antibody was used in Western Blot of Fetal Spleen   tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu WB
50 µg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

RNASEN

RNASEN Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

RNASEN

RNASEN Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

DROSHA overexpression lysate

DROSHA overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

14 Item(s)

per page
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