RNF139 antibody

Principal name

RNF139 antibody

Alternative names for RNF139 antibody

RNF139, TRC8, RING finger protein 139, Translocation in renal carcinoma on chromosome 8

SwissProt ID

Q5RBT7 (Ponab), Q7TMV1 (Mouse), Q8WU17 (Human)

Gene ID

11236 (RNF139)

Available reactivities

Hu (Human), Can (Canine), Bov (Bovine), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Goat, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of RNF139 antibody

RNF139 is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t(3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP. The protein encoded by this gene is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t(3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP.

General readings

Gemmill RM, West JD, Boldog F, Tanaka N, Robinson LJ, Smith DI, Li F, Drabkin HA. The hereditary renal cell carcinoma 3;8 translocation fuses FHIT to a patched-related gene, TRC8. Proc Natl Acad Sci U S A. 1998 Aug 4;95(16):9572-7. PMID: 9689122

14 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

RNF139 (C-term) antibody

TA305669 (0.5ug/ml) staining of Human Skeletal muscle lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Can, Hu E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

RNF139 antibody

WB Suggested Anti-RNF139 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: MCF7 cell lysateRNF139 is supported by BioGPS gene expression data to be expressed in MCF7 Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

RNF139 antibody

RNF139 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

RNF139 antibody

Immunoperoxidase of monoclonal antibody to RNF139 on formalin-fixed paraffin-embedded human tonsil. [antibody concentration 3 ug/ml] Mouse IgG1 3D10 Purified Hu E, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

RNF139 antibody

RNF139 Mouse IgG1 2D5 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

RNF139 antibody

RNF139 polyclonal antibody ( Cat # PAB12810 ) ( 0.5µg/ml ) staining of human skeletal muscle lysate ( 35µg protein in RIPA buffer ). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Hu E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

RNF139 antibody

Human MCF-7; WB Suggested Anti-RNF139 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: MCF7 cell lysate. RNF139 is supported by BioGPS gene expression data to be expressed in MCF7.; RNF139 antibody - N-terminal region (ARP43092_P050) in Human MCF-7 cells using Western Blot Rabbit Aff - Purified Bov, Can, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

RNF139 antibody

Western Blot: Anti-TRC8 Antibody [NBP1-23027]-(0.5ug/ml) staining of Human Skeletal muscle lysate (35ug protein in RIPA buffer) Goat IgG Aff - Purified Hu E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

RNF139 antibody

Western Blot: RNF139 Antibody [NBP1-59756] - This Anti-RNF139 antibody was used in Western Blot of MCF7 tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu, Ms, Rt WB
50 µg / €440.00
  Novus Biologicals Inc.

RNF139 antibody

Immunohistochemistry-Paraffin: RNF139 Antibody [NBP1-83212] - Immunohistochemical staining of human testis shows strong cytoplasmic positivity in cells in seminiferus ducts. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

RNF139

RNF139 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue
10 µg / €380.00
  Abnova Taiwan Corp.

RNF139

RNF139 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue
25 µg / €510.00
  Abnova Taiwan Corp.

RNF139

RNF139 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

RNF139

RNF139 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

14 Item(s)

per page
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