RNF168 antibody

Principal name

RNF168 antibody

Alternative names for RNF168 antibody

RING finger protein 168, E3 ubiquitin-protein ligase RNF168

SwissProt ID

B2RYR0 (Rat), Q0IIM1 (Bovin), Q6INS5 (Xenla), Q7T308 (Danre), Q80XJ2 (Mouse), Q8IYW5 (Human)

Gene ID

165918 (RNF168)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Ms (Mouse), Rt (Rat), African clawed frog

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), EPair for Elisa (EPair)

Background of RNF168 antibody

RNF168 was identified as a chromatin-associated RING finger protein that acts as a ubiquitin ligase both in vitro and in vivo. RNF168 targets histones H2A and H2AX, but not H2B, forming K63 polyubiquitin chains. Upon formation of DNA double strand breaks, RNF168 is recruited to the site of DNA damage where it co-localizes with gammaH2AX and 53BP1 in an RNF8-dependent manner. This localization of RNF168 increases the local concentration of ubiquinated proteins to the threshold required for retention of the proteins 53BP1 and BRCA1, facilitating the downstream signaling cascade. Thus, RNF168 defines a new pathway demonstrating a functional cooperation between E3 ligases in genome maintenance. At least three isoforms of RNF168 are known to exist.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

RNF168 antibody

Western blot analysis of RNF168 in human brain tissue lysate with RNF168 antibody at 1 µg/ml. Rabbit IgG Aff - Purified Hu, Ms E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

RNF168 antibody

WB Suggested Anti-RNF168 Antibody Titration: 0.5 ug/ml; Positive Control: HepG2 cell lysate Rabbit IgG Purified Hu P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

RNF168 Control Peptide

RNF168
50 µg / €160.00
  Acris Antibodies GmbH

RNF168 antibody

Immunofluorescence of purified MaxPab antibody to RNF168 on HeLa cell. [antibody concentration 10 ug/ml] Mouse Purified Hu E(detection), ICC/IF, WB
50 µg / €370.00
  Abnova Taiwan Corp.

RNF168 antibody

RNF168 MaxPab rabbit polyclonal antibody. Western Blot analysis of RNF168 expression in human liver. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

RNF168 antibody

Immunoperoxidase of monoclonal antibody to RNF168 on formalin-fixed paraffin-embedded human prostate cancer. [antibody concentration 1.5 ug/ml] Mouse IgG2b 3E1 Purified Hu E, ICC/IF, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

RNF168 antibody

Human Brain; RNF168 antibody - C-terminal region (ARP43433_P050) in Human Brain cells using Immunohistochemistry Rabbit Aff - Purified African clawed frog, Bov, Can, Chk, Hu, Ms, Rt P, WB
50 µg / €350.00
  AVIVA Systems Biology

RNF168 antibody

Western Blot: RNF168 Antibody [NBP1-55075] - This Anti-RNF168 antibody was used in Western Blot of HepG2 tissue lysate at a concentration of 0.5ug/ml. Rabbit Aff - Purified Can, Hu, Ms, Rt P, WB
50 µg / €440.00
  Novus Biologicals Inc.

RNF168 antibody

Western Blot: RNF168 Antibody [NBP1-76324] - Analysis of RNF168 in human brain tissue lysate with RNF168 antibody at 1 ug/mL._x000d_ Rabbit Aff - Purified Hu, Ms E, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

RNF168

RNF168 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

RNF168

RNF168 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
2 µg / €300.00
  Abnova Taiwan Corp.

RNF168

RNF168 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

RNF168

RNF168 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Antibody Pairs

Catalog No.    

RNF168 (Human) Matched Antibody Pair

RNF168 (Human) Matched Antibody Pair  
1 set / €710.00
  Abnova Taiwan Corp.

RNF168 (Human) Matched Antibody Pair

RNF168 (Human) Matched Antibody Pair  
1 set / €710.00
  Abnova Taiwan Corp.

RNF168 (Human) Matched Antibody Pair

RNF168 (Human) Matched Antibody Pair  
1 set / €710.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

RNF168 293T Cell Transient Overexpression Lysate(Denatured)

RNF168 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

RNF168 overexpression lysate

RNF168 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

18 Item(s)

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