RNF213 antibody

Principal name

RNF213 antibody

Alternative names for RNF213 antibody

RNF213, C17orf27, KIAA1554, RING finger protein 213

SwissProt ID

Q63HN8 (Human)

Gene ID

57674 (RNF213)

Available reactivities

Hu (Human), Rt (Rat), Ms (Mouse)

Available hosts

Mouse, Goat, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of RNF213 antibody

The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made up of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. RNF213 (ring finger protein 213), also known as NET57, is a 3,280 amino acid protein containing one RING-type zinc finger domain through which it may play a role in transcriptional regulation and protein degradation. RNF213 is encoded by a gene located on human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.

General readings

Zody MC et al
DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.
Nature. 2006 Apr 20;440(7087):1045-9.
PMID: 16625196

11 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

RNF213 (C-term) antibody

TA303190 (2.5µg/ml) staining of paraffin embedded human kidney. Steamed antigen retrieval with citrate buffer pH 6, AP-staining Goat Aff - Purified Hu E, P
0.1 mg / €325.00
  OriGene Technologies, Inc.

RNF213 antibody

Host: Rabbit; Target Name: RNF213; Sample Tissue: Thyroid Tumor lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

RNF213 antibody

RNF213 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

RNF213 antibody

RNF213 Mouse IgG2a 5C12 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

RNF213 antibody

RNF213 Goat Hu E
0.1 mg / €390.00
  Abnova Taiwan Corp.

RNF213 antibody

RNF213 polyclonal antibody ( Cat # PAB7507 ) ( 2.5 µg/ml ) staining of paraffin embedded human kidney. Steamed antigen retrieval with citrate buffer pH 6, AP-staining Goat Hu E, P
0.1 mg / €400.00
  Abnova Taiwan Corp.

RNF213 antibody

NB100-55427 (2.5ug/ml) staining of paraffin embedded Human Kidney. Steamed antigen retrieval with citrate buffer pH 6, AP-staining Goat IgG Aff - Purified Rt E, P
0.1 mg / €400.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

RNF213

RNF213 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

RNF213

RNF213 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

RNF213

RNF213 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

RNF213 overexpression lysate

RNF213 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

11 Item(s)

per page
  • LinkedIn