RNF216 antibody

Principal name

RNF216 antibody

Alternative names for RNF216 antibody

RING finger protein 216, TRIAD3, UBCE7IP1, ZIN, E3 ubiquitin-protein ligase RNF216, Triad domain-containing protein 3, Zinc finger protein inhibiting NF-kappa-B, Ubiquitin-conjugating enzyme 7-interacting protein 1

SwissProt ID

P58283 (Mouse), Q8C1U3 (Mouse), Q9NWF9 (Human)

Gene ID

54476 (RNF216), 108086 (Rnf216)

Available reactivities

Ms (Mouse), Hu (Human), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of RNF216 antibody

Activation of NF-kappaB as a result of Toll-like receptor (TLR) and IL-1 receptor signaling is a major component of innate immune responses (reviewed in 1). Signals from these receptors are relayed by a number of adapter molecules such as TRIF, TIRAP, and MyD88 (2). Several regulatory mechanisms exist to control TLR signal transduction, including the inhibition of TLR expression and signaling by molecules such as ST2 and SIGIRR (3,4). Another mechanism is by the ubi-quitinization of selected TLRs by TRIAD3A, an E3 ubiquitin-protein ligase (5). TRIAD3A is a RING finger protein that can bind to TLR4 and TLR9, and to a lesser extent TLR3 and TLR5, catalyzing the ubiquitization of these molecules. Overexpression of TRIAD3A promoted the nearly complete degradation of TLR4 and TLR9; this reduction was reflected in the decreased signal-specific activation by ligands specific for these TLRs. Conversely, depletion of TRIAD3A resulted in enhanced TLR activation (5).

17 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

RNF216 antibody

Western blot analysis of TRIAD3A in mouse heart cell lysates with TRIAD3A antibody at (A) 0.5, (B) 1, and (C) 2 ug/ml. Rabbit IgG Purified Hu, Ms E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

RNF216 antibody

Host: Rabbit; Target Name: Rnf216; Sample Tissue: Mouse Thymus lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

RNF216 (Isoform 1) antibody

Western blot analysis of TRIAD3A in mouse heart cell lysates with TRIAD3A antibody at (A) 0.5, (B) 1, and (C) 2 µg/ml Rabbit IgG Purified Ms WB
0.1 mg / €370.00
  Acris Antibodies GmbH

RNF216 antibody

Testis: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit Purified Ms P, WB
50 µg / €470.00
  Acris Antibodies GmbH

RNF216 (350-400) antibody

Liver: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit IgG Aff - Purified Hu P, WB
50 µg / €470.00
  Acris Antibodies GmbH

RNF216 (C-term) antibody

Formalin-fixed and paraffin-embedded human breast carcinoma reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Purified Hu, Ms P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

RNF216 Control Peptide

RNF216
50 µg / €160.00
  Acris Antibodies GmbH

RNF216 (N-term) antibody

Formalin fixed, paraffin embedded mouse heart stained with Rabbit anti Mouse TRIAD3A (SP2172P) following antigen retrieval using sodium citrate buffer (pH6.0) Rabbit Purified Ms P, WB
0.1 mg / €400.00
  Acris Antibodies GmbH

RNF216 (N-term) antibody

Formalin fixed, paraffin embedded mouse heart stained with Rabbit anti Mouse TRIAD3A (SP2172P) following antigen retrieval using sodium citrate buffer (pH6.0) Rabbit IgG Purified Ms P, WB
50 µg / €300.00
  Acris Antibodies GmbH

RNF216 antibody

RNF216 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

RNF216 antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with RNF216 polyclonal antibody ( Cat # PAB1762 ) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma. Rabbit Hu, Ms E, P, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

RNF216 antibody

Western blot analysis of Rnf216 expression in mouse heart tissue with Rnf216 polyclonal antibody at 0.5 µg/ml. Rabbit Ms WB
0.1 mg / €470.00
  Abnova Taiwan Corp.

RNF216 antibody

Immunohistochemistry of Rnf216 in mouse heart with Rnf216 polyclonal antibody ( Cat # PAB12931 ) at 10 µg/ml. Rabbit Ms P, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

RNF216 antibody

RNF216 Rabbit IgG Aff - Purified Ms P, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

RNF216 antibody

RNF216 Rabbit Aff - Purified Ms P, WB
50 µg / €480.00
  Novus Biologicals Inc.

RNF216 antibody

Immunohistochemistry-Paraffin: TRIAD3 Antibody [NBP1-86906] - Immunohistochemical staining of human testis shows strong cytoplasmic positivity in developing sperm cells. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

RNF216 antibody

Immunohistochemistry-Paraffin: TRIAD3 Antibody [NBP1-86907] - Immunohistochemical staining of human small intestine shows moderate positivity in glandular cells. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

17 Item(s)

per page
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